COMPARISON OF THE EFFECT OF BUPIVACAINE-FENTANYL AND BUPIVACAINE – NEOSTIGMINE WITH BUPIVACAINE ALONE IN PEDIATRIC CAUDAL BLOCK

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MIRESKANDARI S.M.; DARABI M.E.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2005 | Volume:27 | Issue:52 Page(s): 37-45

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Title

COMPARISON OF THE EFFECT OF BUPIVACAINE-FENTANYL AND BUPIVACAINE – NEOSTIGMINE WITH BUPIVACAINE ALONE IN PEDIATRIC CAUDAL BLOCK

Author(s)

MIRESKANDARI S.M. | DARABI M.E. | Issue Writer Certificate

Keywords

CAUDAL BLOCKQ3

PEDIATRICSQ3

BUPIVACAINEQ2

FENTANYLQ4

NEOSTIGMINQ3

Abstract

Background: CAUDAL BLOCK with local anesthetic agents has been extensively used in pediatric patients to provide intra and postoperative analgesia for surgical procedures such as herniorrhaphy or orchidopexy. Various additives to local anesthetic solutions have been used to prolong and enhance analgesia after CAUDAL BLOCK. The aim of this study was to evaluate effectiveness of BUPIVACAINE 0.25% with the addition of FENTANYL or NEOSTIGMINe for CAUDAL BLOCK in children undergoing inguinal herniorrhaphy. Materials & Methods: 75 children were randomly allocated to three groups to receive a CAUDAL BLOCK with either 0.75 ml/kg BUPIVACAINE, 0.25% with 1mg/kg NEOSTIGMINe (group BN), or 1µg/kg FENTANYL (group SF) or 0.75ml/kg BUPIVACAINE 0.25% alone (group B). Haemodynamic variables, degrees of pain and sedation, additional analgesic requirments, and side effects were evaluated. Mean age, weight and duration of anesthesia and surgery were similar in the three groups. Baseline systolic arterial pressure and heart rate were silmilar in the three groups.Results: Mean intraoperative systolic arterial pressure and heart rate were higher in group B than the other groups, but this was not statistically significant. Adequate analgesia was obtained in 21 (84%) patients in group B, 23 (92%) in group BN and group BF. This difference was not significant. There was no difference in degree of sedation and analgesia between the groups. The incidence of vomiting was similar between the groups. No other side effects were seen.Conclusion: We found that addition of 1µg/kg FENTANYL or 1mg/kg NEOSTIGMINe to 0.75ml/kg BUPIVACAINE 0.25% provide no further analgesic advantage when compared to 0.75 ml/kg BUPIVACAINE of 0.25% alone in CAUDAL BLOCK in children undergoing unilateral herniorraphy.

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APA: Copy

MIRESKANDARI, S.M., & DARABI, M.E.. (2005). COMPARISON OF THE EFFECT OF BUPIVACAINE-FENTANYL AND BUPIVACAINE – NEOSTIGMINE WITH BUPIVACAINE ALONE IN PEDIATRIC CAUDAL BLOCK. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 27(52), 37-45. SID. https://sid.ir/paper/63443/en

Vancouver: Copy

MIRESKANDARI S.M., DARABI M.E.. COMPARISON OF THE EFFECT OF BUPIVACAINE-FENTANYL AND BUPIVACAINE – NEOSTIGMINE WITH BUPIVACAINE ALONE IN PEDIATRIC CAUDAL BLOCK. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2005;27(52):37-45. Available from: https://sid.ir/paper/63443/en

IEEE: Copy

S.M. MIRESKANDARI, and M.E. DARABI, “COMPARISON OF THE EFFECT OF BUPIVACAINE-FENTANYL AND BUPIVACAINE – NEOSTIGMINE WITH BUPIVACAINE ALONE IN PEDIATRIC CAUDAL BLOCK,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 27, no. 52, pp. 37–45, 2005, [Online]. Available: https://sid.ir/paper/63443/en

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