INTERRELATION BTWEEN MANGANESE AND IRON METABOLISM IN RAT (IN VIVO STUDIES)

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HASSANZADEH GHASABEH T.; MOSHTAGHI A.A.

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Journal: Studies in Medical Sciences Year:2002 | Volume:13 | Issue:3 Page(s): 205-212

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Title

INTERRELATION BTWEEN MANGANESE AND IRON METABOLISM IN RAT (IN VIVO STUDIES)

Author(s)

HASSANZADEH GHASABEH T. | MOSHTAGHI A.A. | Issue Writer Certificate

Keywords

MANGANESEQ3

IRONQ3

TRACE ELEMENTSQ3

Abstract

Introduction: MANGANESE is an essential trace element. There is a little evidence for deficiency of MANGANESE in human. Whereas its toxicity has been reported in several cases. MANGANESE toxicity occurs in humans exposed to high environmental concentrations (for example workers in the dry battery industries) and may be particularly important in the neonatal period. The chemical similarities between MANGANESE and IRON, may lead to the disturbances of IRON metabolism. Therefore, the interference of Mn with Fe metabolism by In vivo studies, has been investigated. Methods & Material: In the present project, we used rats. Injection of MANGANESE was carried out by using MnCl2 4H2O, with cancentration 100 mg/ml. Seven group of male rats were selected, so that each group included five rat and MANGANESE injected in their perituneum. Results: The data of this study indicate that factors such as serum IRON; TIBC; UIBC and pure transferring reduced to 9-40 percent, whereas serum MANGANESE significantly elevated. Thus, MANGANESE can interference with IRON metabolism. Discussion: The data that has been presented in this article elucidated the probable mechanism by which Mn interference with Fe metabolism; which result in the appearance of anemia.

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References

MANGANESE INTERFERENCE WITH IRON ABSORPTION BY EVERTEDGUT SAC

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APA: Copy

HASSANZADEH GHASABEH, T., & MOSHTAGHI, A.A.. (2002). INTERRELATION BTWEEN MANGANESE AND IRON METABOLISM IN RAT (IN VIVO STUDIES). STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 13(3), 205-212. SID. https://sid.ir/paper/63519/en

Vancouver: Copy

HASSANZADEH GHASABEH T., MOSHTAGHI A.A.. INTERRELATION BTWEEN MANGANESE AND IRON METABOLISM IN RAT (IN VIVO STUDIES). STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2002;13(3):205-212. Available from: https://sid.ir/paper/63519/en

IEEE: Copy

T. HASSANZADEH GHASABEH, and A.A. MOSHTAGHI, “INTERRELATION BTWEEN MANGANESE AND IRON METABOLISM IN RAT (IN VIVO STUDIES),” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 13, no. 3, pp. 205–212, 2002, [Online]. Available: https://sid.ir/paper/63519/en

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