EFFECT OF VITAMIN D SUPPLEMENTATION ON THE BLOOD PRESSURE IN PREDIABETIC ADULTS: A RANDOMIZED CLINICAL TRIAL

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GHASSEMI FARZANEH; AYREMLOU PARVIN; ZARRIN RASOUL

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Journal: Studies in Medical Sciences Year:2017 | Volume:27 | Issue:11 Page(s): 1003-1011

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Title

EFFECT OF VITAMIN D SUPPLEMENTATION ON THE BLOOD PRESSURE IN PREDIABETIC ADULTS: A RANDOMIZED CLINICAL TRIAL

Author(s)

GHASSEMI FARZANEH | AYREMLOU PARVIN | ZARRIN RASOUL | Issue Writer Certificate

Keywords

VITAMIN D SUPPLEMENTATIONQ1

PREDIABETESQ1

SYSTOLIC BLOOD PRESSUREQ1

DIASTOLIC BLOOD PRESSUREQ1

Abstract

Background & Aims: Vitamin D plays several important roles in human body. Studies showed that low serum 25 (OH) D results in hyperglycemia, hypertension and cardiovascular disease. The objective of current study was to examine the effect of 3-month supplementation with 1000IU vitamin D on blood pressure in prediabetic adults.Materials & Methods: In a 3 month randomized clinical trial, 120 eligible subjects were randomly assigned to vitamin D or placebo group; they were stratified according to percentage of body fat mass in four blocks to receive 1000 IU/daily vitamin D or an identical placebo tablet for 3 months, respectively. Participants were adults aged 18-70 years old with PREDIABETES. SYSTOLIC BLOOD PRESSURE (SBP), DIASTOLIC BLOOD PRESSURE (DBP), serum 25 (OH) D levels, BMI, waste circumference, percentage of body fat mass (FM), physical activity, sun exposure, energy and macro nutrient intake were assessed before and after the intervention.Results: In the intervention group serum levels of 25 (OH) D increased significantly (from19.36 to 30.48, P<0.001); SYSTOLIC BLOOD PRESSURE decreased in vitamin D group significantly (p=0.002), but the changes from baseline was not significantly different between the vitamin D and placebo group.Conclusion: The daily supplementation of 1000IU vitamin D for 3 months has no effect on the blood pressure.

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APA: Copy

GHASSEMI, FARZANEH, AYREMLOU, PARVIN, & ZARRIN, RASOUL. (2017). EFFECT OF VITAMIN D SUPPLEMENTATION ON THE BLOOD PRESSURE IN PREDIABETIC ADULTS: A RANDOMIZED CLINICAL TRIAL. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 27(11), 1003-1011. SID. https://sid.ir/paper/63705/en

Vancouver: Copy

GHASSEMI FARZANEH, AYREMLOU PARVIN, ZARRIN RASOUL. EFFECT OF VITAMIN D SUPPLEMENTATION ON THE BLOOD PRESSURE IN PREDIABETIC ADULTS: A RANDOMIZED CLINICAL TRIAL. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2017;27(11):1003-1011. Available from: https://sid.ir/paper/63705/en

IEEE: Copy

FARZANEH GHASSEMI, PARVIN AYREMLOU, and RASOUL ZARRIN, “EFFECT OF VITAMIN D SUPPLEMENTATION ON THE BLOOD PRESSURE IN PREDIABETIC ADULTS: A RANDOMIZED CLINICAL TRIAL,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 27, no. 11, pp. 1003–1011, 2017, [Online]. Available: https://sid.ir/paper/63705/en

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