مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

345
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

177
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

AN IN VIVO AND IN VITRO INVESTIGATION ON HEPATOPROTECTIVE EFFECTS OF PIMPINELLA ANISUM SEED ESSENTIAL OIL AND EXTRACTS AGAINST CARBON TETRACHLORIDE-INDUCED TOXICITY

Pages

  205-211

Keywords

CCL4 
HEPG2 CELLS 
RAT 

Abstract

 Objective(s): Protective effects of different extracts and essential oil from Pimpinella anisum L. seeds were examined against carbon tetrachloride (CCl4)-induced toxicity. The parameters such as serum transaminases, lactate dehydrogenase activity, hepatic glutathione content, liver lipid peroxidation and histopathological changes of liver were assessed as toxicity markers. In the in vitro model of this study, markers such as cell viability, cellular reduced and oxidized glutathione and lipid peroxidation in HepG2 cells were evaluated.Materials and Methods: Human liver cancer cell line HepG2 and male Sprague-Dawley RATs were treated with extracts and essential oil, and markers of HEPATOTOXICITY were investigated.Results: The data revealed that the n-hexane extract, effectively attenuated CCl4-induced toxicity in both in vitro and in vivo models in current investigation.Conclusion: As the OXIDATIVE STRESS markers were ameliorated, it might be concluded that ANISE SEED possesses protective effects probably due to its antioxidant constituents.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    JAMSHIDZADEH, AKRAM, HEIDARI, REZA, RAZMJOU, MOJTABA, KARIMI, FOROUZAN, MOEIN, MAHMOOD REZA, FARSHAD, OMID, AKBARIZADEH, AMIN REZA, & HOUSHANGI SHAYESTEH, MOHAMMAD REZA. (2015). AN IN VIVO AND IN VITRO INVESTIGATION ON HEPATOPROTECTIVE EFFECTS OF PIMPINELLA ANISUM SEED ESSENTIAL OIL AND EXTRACTS AGAINST CARBON TETRACHLORIDE-INDUCED TOXICITY. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 18(2), 205-211. SID. https://sid.ir/paper/638266/en

    Vancouver: Copy

    JAMSHIDZADEH AKRAM, HEIDARI REZA, RAZMJOU MOJTABA, KARIMI FOROUZAN, MOEIN MAHMOOD REZA, FARSHAD OMID, AKBARIZADEH AMIN REZA, HOUSHANGI SHAYESTEH MOHAMMAD REZA. AN IN VIVO AND IN VITRO INVESTIGATION ON HEPATOPROTECTIVE EFFECTS OF PIMPINELLA ANISUM SEED ESSENTIAL OIL AND EXTRACTS AGAINST CARBON TETRACHLORIDE-INDUCED TOXICITY. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2015;18(2):205-211. Available from: https://sid.ir/paper/638266/en

    IEEE: Copy

    AKRAM JAMSHIDZADEH, REZA HEIDARI, MOJTABA RAZMJOU, FOROUZAN KARIMI, MAHMOOD REZA MOEIN, OMID FARSHAD, AMIN REZA AKBARIZADEH, and MOHAMMAD REZA HOUSHANGI SHAYESTEH, “AN IN VIVO AND IN VITRO INVESTIGATION ON HEPATOPROTECTIVE EFFECTS OF PIMPINELLA ANISUM SEED ESSENTIAL OIL AND EXTRACTS AGAINST CARBON TETRACHLORIDE-INDUCED TOXICITY,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 18, no. 2, pp. 205–211, 2015, [Online]. Available: https://sid.ir/paper/638266/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button