PATHOLOGICAL EFFECTS OF CHROMIUM ON RAT LIVER TISSUE

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MOSHTAGHI SEYED ALI ASGHAR; RAJABI P.; ESMAEILI A.H.

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Journal: Studies in Medical Sciences Year:2002 | Volume:13 | Issue:1 Page(s): 1-7

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Title

PATHOLOGICAL EFFECTS OF CHROMIUM ON RAT LIVER TISSUE

Author(s)

MOSHTAGHI SEYED ALI ASGHAR | RAJABI P. | ESMAEILI A.H. | Issue Writer Certificate

Keywords

CHROMIUMQ4

TOXICITYQ3

LIVERQ2

Abstract

Introduction: CHROMIUM is necessary for carbohydrate and lipid metabolism. CHROMIUM (ІІІ) is necessary for the activation of Insulin secretion and it is used for the treatment of NIDDM in very low concentration. It produces TOXICITY particulary in Nuclear hepatocytes in high concentration. In this project the acute and chronic effects of CHROMIUM on rat LIVER tissue has been investigated. Methods: Rats were divided into two groups. In one group 2mg/kg CHROMIUM were injected daily for 30 and 60 days and in another group 400 mg/kg of CHROMIUM administered for one day Rat were anesthetized with ether and their LIVER were removed for microscopic examinations. Results: results obtained show that intraperitoneal administration of 2mg CHROMIUM for 30 days causes vascular, fibrosis (+2) and intermediate fibrosis and inflammation of vascular (+3). Administration of 400 mg\kg of CHROMIUM causes secretion of lymphocytes and accumulation of neutrophil.Discussion: CHROMIUM is an essential element in low concentration and toxic particulary at very high concentration.

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APA: Copy

MOSHTAGHI, SEYED ALI ASGHAR, RAJABI, P., & ESMAEILI, A.H.. (2002). PATHOLOGICAL EFFECTS OF CHROMIUM ON RAT LIVER TISSUE. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 13(1), 1-7. SID. https://sid.ir/paper/63928/en

Vancouver: Copy

MOSHTAGHI SEYED ALI ASGHAR, RAJABI P., ESMAEILI A.H.. PATHOLOGICAL EFFECTS OF CHROMIUM ON RAT LIVER TISSUE. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2002;13(1):1-7. Available from: https://sid.ir/paper/63928/en

IEEE: Copy

SEYED ALI ASGHAR MOSHTAGHI, P. RAJABI, and A.H. ESMAEILI, “PATHOLOGICAL EFFECTS OF CHROMIUM ON RAT LIVER TISSUE,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 13, no. 1, pp. 1–7, 2002, [Online]. Available: https://sid.ir/paper/63928/en

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