THE FREQUENCY OF ANTIBIOTIC RESISTANCE AND CTX-M GENE IN ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS OF OUT-PATIENTS IN KERMANSHAH

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHODADOOST MEHRDAD; AKYA ALISHA; ALE TAHA SEYED MANSOUR; ADABAGHER SHIRRIN

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Studies in Medical Sciences Year:2013 | Volume:24 | Issue:5 Page(s): 318-328

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

653

Download:

Cites:

Information Journal Paper

Title

THE FREQUENCY OF ANTIBIOTIC RESISTANCE AND CTX-M GENE IN ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS OF OUT-PATIENTS IN KERMANSHAH

Author(s)

KHODADOOST MEHRDAD | AKYA ALISHA | ALE TAHA SEYED MANSOUR | ADABAGHER SHIRRIN | Issue Writer Certificate

Keywords

URINARY TRACT INFECTIONQ3

ESCHERICHIA COLIQ2

CTX-MQ2

Abstract

Background & Aims: One of the most prevalent bacterial infections is URINARY TRACT INFECTION (UTI), and ESCHERICHIA COLI has been isolated from 75-90 percent of UTI cases. On the other hand, the rate of community acquired UTI caused by extended spectrum beta-lactamase producing E. coli, in particular bla CTX-M is increasing worldwide. Therefore, this study aimed to assess the pattern of antibiotic resistance, ESBL frequency, and bla CTX-M gene in E. coli isolated from UTI of out-patients.Materials & Methods: This study was carried out on the urinary samples of out-patients and 140 E.colistrains isolated. Then the susceptibility of isolates to 10 selected antibiotics was tested using disc diffusion method. Later, the ESBL producer strains were confirmed using combined discs method.Finally, the blaCTX-M gene was determined in ESBL producer isolates using PCR.Results: Of 140 isolates, 81.43 % and 62.13% showed resistance to ampicillin and Co-trimoxazole, respectively, but 100% were sensitive to imipenem. Moreover, 34 (24.28%) isolates were ESBL producers. PCR showed that 30 (88%) of ESBL producer isolates contained CTX-M gene.Conclusion: Resistance to various beta-lactam antibiotics in particular the third generation of cephalosporins is a serious concern. The production of ESBL, in particular in isolates of out-patients, is a big threat for use of the broad spectrum cephalosporins. Given the presence of CTX-M gene in the high proportion of the isolates, more molecular and epidemiological studies on pathogenic bacteria in this region is required.

Cites

No record.

References

No record.

Cite

APA: Copy

KHODADOOST, MEHRDAD, AKYA, ALISHA, ALE TAHA, SEYED MANSOUR, & ADABAGHER, SHIRRIN. (2013). THE FREQUENCY OF ANTIBIOTIC RESISTANCE AND CTX-M GENE IN ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS OF OUT-PATIENTS IN KERMANSHAH. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 24(5), 318-328. SID. https://sid.ir/paper/63938/en

Vancouver: Copy

KHODADOOST MEHRDAD, AKYA ALISHA, ALE TAHA SEYED MANSOUR, ADABAGHER SHIRRIN. THE FREQUENCY OF ANTIBIOTIC RESISTANCE AND CTX-M GENE IN ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS OF OUT-PATIENTS IN KERMANSHAH. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2013;24(5):318-328. Available from: https://sid.ir/paper/63938/en

IEEE: Copy

MEHRDAD KHODADOOST, ALISHA AKYA, SEYED MANSOUR ALE TAHA, and SHIRRIN ADABAGHER, “THE FREQUENCY OF ANTIBIOTIC RESISTANCE AND CTX-M GENE IN ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS OF OUT-PATIENTS IN KERMANSHAH,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 24, no. 5, pp. 318–328, 2013, [Online]. Available: https://sid.ir/paper/63938/en

Related Journal Papers