EFFICACY OF NIFEDIPINE VERSUS MAGNESIUM SULFATE IN THE MANAGEMENT OF PRETERM LABOR

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NIROUMANESH SHIRIN; ABEDI F.

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Journal: Studies in Medical Sciences Year:2001 | Volume:12 | Issue:1 Page(s): 8-15

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Title

EFFICACY OF NIFEDIPINE VERSUS MAGNESIUM SULFATE IN THE MANAGEMENT OF PRETERM LABOR

Author(s)

NIROUMANESH SHIRIN | ABEDI F. | Issue Writer Certificate

Keywords

NIFEDIPINEQ4

MAGNESIUM SULFATEQ3

PRETERM TABORQ3

Abstract

This study compares the efficacy of NIFEDIPINE with MAGNESIUM SULFATE in arresting preterm labor. Forty six singleton pregnancies with preterm labor were assigned randomly to either MAGNESIUM SULFATE intravenously (n=23) or NIFEDIPINE prally (n=23). The principal outcome assessed was delay of delivery.Both drugs were equally effective in arresting labor and delaying delivery up to 48 hours (78% versus 91% p=NS) to one week (65% versus 73%, p=NS) and to term (52% versus 61%, p=NS) There were significantly fewer maternal side effects in the NIFEDIPINE group (39% versus 74% p=0.03), and duration of maternal hospitalization in the NIFEDIPINE group was shorter than MAGNESIUM SULFATE group (2.65 versus 5.7 days, p=0.007) Apgar scores were similar in both groups the MAGNESIUM SULFATE (17% versus zero, p=0.03).These resuits suggest that oral NIFEDIPINE is as effective as MAGNESIUM SULFATE in arresting PRETERM TABOR, and is significantly associated with fewer maternal side effects, and fewer admissions to the NICU.

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APA: Copy

NIROUMANESH, SHIRIN, & ABEDI, F.. (2001). EFFICACY OF NIFEDIPINE VERSUS MAGNESIUM SULFATE IN THE MANAGEMENT OF PRETERM LABOR. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 12(1), 8-15. SID. https://sid.ir/paper/64051/en

Vancouver: Copy

NIROUMANESH SHIRIN, ABEDI F.. EFFICACY OF NIFEDIPINE VERSUS MAGNESIUM SULFATE IN THE MANAGEMENT OF PRETERM LABOR. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2001;12(1):8-15. Available from: https://sid.ir/paper/64051/en

IEEE: Copy

SHIRIN NIROUMANESH, and F. ABEDI, “EFFICACY OF NIFEDIPINE VERSUS MAGNESIUM SULFATE IN THE MANAGEMENT OF PRETERM LABOR,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 12, no. 1, pp. 8–15, 2001, [Online]. Available: https://sid.ir/paper/64051/en

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