STUDY OF THE EFFECTS OF HALOTHANE THE LIVER FUNCTIONAL TESTS DURING PROLONGED ANESTHESIA

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ASADI LOUYEH A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Studies in Medical Sciences Year:2001 | Volume:12 | Issue:2 Page(s): 147-153

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Title

STUDY OF THE EFFECTS OF HALOTHANE THE LIVER FUNCTIONAL TESTS DURING PROLONGED ANESTHESIA

Author(s)

ASADI LOUYEH A. | Issue Writer Certificate

Keywords

HALOTHANEQ4

MAINTENANCE PHASEQ4

PROLONGED ANESTHESIAQ4

PT CHANGESQ4

Abstract

Introduction: HALOTHANE is one of the inhalation anesthetic drugs which is commonly used for MAINTENANCE PHASE of anesthesia in Iran. It is used via repiratory tract and is excreted by two mechanisms. Firstly, it is excreted through respiratory tract without any changes. The second way is by the liver involvement that HALOTHANE changes to secondary active metabolites, which are more hepatotoxic.Materials & Methods: This quasi experimental study carried out on 50 patients who were randomly selected. These patients received PROLONGED ANESTHESIA using HALOTHANE as a major anesthetic drug for MAINTENANCE PHASE. They were examined before and 24 hours after operation and their PT, PIT, AST and ALT were recorded.Results: The results showed that only the average of PT before and 24 hours after operation was significantly different (P<0.001). Discussion: The PT CHANGES were directly related to the time of exposure with HALOTHANE, blood iransfusion during operation and also the patients' gender (young males). No significant relationship was observed with the concentration of HALOTHANE during operation.

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APA: Copy

ASADI LOUYEH, A.. (2001). STUDY OF THE EFFECTS OF HALOTHANE THE LIVER FUNCTIONAL TESTS DURING PROLONGED ANESTHESIA. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 12(2), 147-153. SID. https://sid.ir/paper/64164/en

Vancouver: Copy

ASADI LOUYEH A.. STUDY OF THE EFFECTS OF HALOTHANE THE LIVER FUNCTIONAL TESTS DURING PROLONGED ANESTHESIA. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2001;12(2):147-153. Available from: https://sid.ir/paper/64164/en

IEEE: Copy

A. ASADI LOUYEH, “STUDY OF THE EFFECTS OF HALOTHANE THE LIVER FUNCTIONAL TESTS DURING PROLONGED ANESTHESIA,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 12, no. 2, pp. 147–153, 2001, [Online]. Available: https://sid.ir/paper/64164/en

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