EFFECTS OF PROBIOTIC YOGURT CONSUMPTION ON LIPID PROFILE IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CONTROLLED CLINICAL TRIAL

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MOHAMMAD SHAHI MAJID; VEISSI MASOUD; HAIDARI FATEMEH; ZARE JAVID AHMAD; MOHAMMADI FATEMEH; SHIRBEIGI ESMAT

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2014 | Volume:19 | Issue:6 Page(s): 531-536

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Title

EFFECTS OF PROBIOTIC YOGURT CONSUMPTION ON LIPID PROFILE IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CONTROLLED CLINICAL TRIAL

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Keywords

LIPID PROFILE

PROBIOTIC YOGURT

TYPE 2 DIABETES

Abstract

Background: Alteration in plasma lipid and lipoprotein profile has been documented in diabetic patients. The purpose of this study was to compare the effect of probiotic and conventional yogurt on LIPID PROFILE in TYPE 2 DIABETES mellitus patients.Materials and Methods: A total of 44 patients with TYPE 2 DIABETES aged 30-60 years old who had low density lipoprotein cholesterol (LDL-c) ³100 mg/dl enrolled in this randomized, double – blind controlled trial and were assigned to two intervention and control groups. The subjects in the intervention group consumed 300 g/d PROBIOTIC YOGURT containing Lactobacillus acidophilus La-5 and Bifi dobacterium lactis Bb-12 and subjects in the control group consumed 300 g/d conventional yogurt for 8 weeks. Anthropometric indices, dietary intake, and serum LIPID PROFILE were evaluated at the beginning and end of the intervention. Independent-sample t-test, paired sample t-test, ANCOVA, and repeated measures were used for statistical analysis.Results: The consumption of PROBIOTIC YOGURT caused significant decrease in LDL-c/high density lipoprotein cholesterol (HDL-c) ratio (3.13±1.00-2.07±0.71, P=0.016). The levels of HDL-c were increased significantly (43.66±6.80-50.42±6.64, P=0.023) in the intervention group post intervention. However, there were no significant differences in triglyceride and total cholesterol levels between two groups post intervention (P < 0.05).Conclusion: It is suggested that PROBIOTIC YOGURT consumption may be used as an alternative prevention approach and treatment method to improve dyslipidemia in patients with TYPE 2 DIABETES.

Cites

THE EFFECT OF DIFFERENT CONCENTRATIONS OF VITAMIN D3, CUMINUM CYMINUM ESSENTIAL OIL, AND FERMENTATION TIME USING RESPONSE SURFACE METHODOLOGY ON THE OPTIMIZATION OF PROBIOTIC YOGURT

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APA: Copy

MOHAMMAD SHAHI, MAJID, VEISSI, MASOUD, HAIDARI, FATEMEH, ZARE JAVID, AHMAD, MOHAMMADI, FATEMEH, & SHIRBEIGI, ESMAT. (2014). EFFECTS OF PROBIOTIC YOGURT CONSUMPTION ON LIPID PROFILE IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CONTROLLED CLINICAL TRIAL. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 19(6), 531-536. SID. https://sid.ir/paper/644524/en

Vancouver: Copy

MOHAMMAD SHAHI MAJID, VEISSI MASOUD, HAIDARI FATEMEH, ZARE JAVID AHMAD, MOHAMMADI FATEMEH, SHIRBEIGI ESMAT. EFFECTS OF PROBIOTIC YOGURT CONSUMPTION ON LIPID PROFILE IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CONTROLLED CLINICAL TRIAL. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2014;19(6):531-536. Available from: https://sid.ir/paper/644524/en

IEEE: Copy

MAJID MOHAMMAD SHAHI, MASOUD VEISSI, FATEMEH HAIDARI, AHMAD ZARE JAVID, FATEMEH MOHAMMADI, and ESMAT SHIRBEIGI, “EFFECTS OF PROBIOTIC YOGURT CONSUMPTION ON LIPID PROFILE IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CONTROLLED CLINICAL TRIAL,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 19, no. 6, pp. 531–536, 2014, [Online]. Available: https://sid.ir/paper/644524/en

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