NEW HORIZONS ON PREVENTION OF PERINATAL TRANSMISSION OF HEPATITIS B

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SIMA H.R.; RAZAVI SETVATI N.; POURJAVAD M.; ADIBI P.

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Paper Information

Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2003 | Volume:6 | Issue:2 Page(s): 86-94

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Title

NEW HORIZONS ON PREVENTION OF PERINATAL TRANSMISSION OF HEPATITIS B

Author(s)

SIMA H.R. | RAZAVI SETVATI N. | POURJAVAD M. | ADIBI P. | Issue Writer Certificate

Keywords

HEPATITIS BQ3

PERINATAL TRANSMISSIONQ4

PREVENTIONQ2

IMMUNIZATIONQ4

Abstract

Objective: HEPATITIS B virus (HBV) infection is a global public health problem; HBV infects 1.5 to 2.5 percent of the general population in Iran. Current therapies do not cause sustained response in all patients, so PREVENTION is the most effective strategy for the disease control. Perinatal infection is one of the predominant modes of transmission in developing countries including Iran, and also associated with high chronicity rate of infection in neonates. Maternal-infant transmission occurs mostly at birth, but it occurs transplacentally during pregnancy in 5 to 10 percent of cases. The risk of maternal-fetal transmission is related to gestational age, HBV replication status and viral load of the mother. Although at present maternal screening and neonatal passive-active IMMUNIZATION was proved to be the most effective method for PREVENTION of vertical transmission, it is not effective in 5 to 10 percent of cases. Recently, viral load lowering and early immunity modulation of fetus methods were described. In the present article, we will point to some of these modalities such as third trimesrter Lamivudine therapy, HBIG administration and in-utero DNA vaccination.

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APA: Copy

SIMA, H.R., RAZAVI SETVATI, N., POURJAVAD, M., & ADIBI, P.. (2003). NEW HORIZONS ON PREVENTION OF PERINATAL TRANSMISSION OF HEPATITIS B. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 6(2), 86-94. SID. https://sid.ir/paper/64546/en

Vancouver: Copy

SIMA H.R., RAZAVI SETVATI N., POURJAVAD M., ADIBI P.. NEW HORIZONS ON PREVENTION OF PERINATAL TRANSMISSION OF HEPATITIS B. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2003;6(2):86-94. Available from: https://sid.ir/paper/64546/en

IEEE: Copy

H.R. SIMA, N. RAZAVI SETVATI, M. POURJAVAD, and P. ADIBI, “NEW HORIZONS ON PREVENTION OF PERINATAL TRANSMISSION OF HEPATITIS B,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 6, no. 2, pp. 86–94, 2003, [Online]. Available: https://sid.ir/paper/64546/en

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