COMPARISON OF INTRA VAGINAL MISOPROSTOL WITH LOW- DOSE OXYTOCIN FOR CERVICAL RIPENING

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DEHGANI FIROZ ABADI R.; GHANE A.; TAYEBI N.

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Title

COMPARISON OF INTRA VAGINAL MISOPROSTOL WITH LOW- DOSE OXYTOCIN FOR CERVICAL RIPENING

Author(s)

DEHGANI FIROZ ABADI R. | GHANE A. | TAYEBI N. | Issue Writer Certificate

Keywords

OXYTOCINQ3

MISOPROSTOLQ2

LABOR INDUCTIONQ3

Abstract

Introduction: Applying mechanical or pharmacological techniques before onset of spontaneous labor condition of cervix is important to the success of LABOR INDUCTION. Because of the efficacy and safety of OXYTOCIN, it is the most common prescribed drug all over the world. Other medical preparations proposed to cervical ripening are prostaglandins such as MISOPROSTOL a synthetic prostaglandin E1. The aim of this study was to compare efficacy of mosoprostol and low-dose OXYTOCINe in cervix ripening and LABOR INDUCTION. Methods and Material: This study was a clinical trial study on 100 pregnant women in Yazd Shahid Sadeghi Hospital in 2003-2005. They all had singletone fetus with GA>37 weeks, and unripped cervix and indications for LABOR INDUCTION. All of data were gathered in the questionnaire. Then, they were analyzed by chi-square, T test and Fisher exact tests. Results: The patients' demographic finding for the groups and indication of LABOR INDUCTION had not significant difference. The time-length between onset of ripening to delivery for MISOPROSTOL group was 20.6±2.6 hours and for low dose OXYTOCIN group was 25.1±2.5 hours (p=0.001). There was no singnificant difference in kind of delivery between two groups (p=0.93). There was singnificant difference between two groups about consumption of magnesium sulfate. It was more in MISOPROSTOL group compared to low dose OXYTOCIN group (p=0.001).Conclusion: Vaginal MISOPROSTOL (25mg/Q4h) is a safe and useful medicine for cervical ripening in low risk patients. It has not any serious side effects for mother and fetus.

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APA: Copy

DEHGANI FIROZ ABADI, R., GHANE, A., & TAYEBI, N.. (2007). COMPARISON OF INTRA VAGINAL MISOPROSTOL WITH LOW- DOSE OXYTOCIN FOR CERVICAL RIPENING. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 10(1), 1-8. SID. https://sid.ir/paper/64600/en

Vancouver: Copy

DEHGANI FIROZ ABADI R., GHANE A., TAYEBI N.. COMPARISON OF INTRA VAGINAL MISOPROSTOL WITH LOW- DOSE OXYTOCIN FOR CERVICAL RIPENING. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2007;10(1):1-8. Available from: https://sid.ir/paper/64600/en

IEEE: Copy

R. DEHGANI FIROZ ABADI, A. GHANE, and N. TAYEBI, “COMPARISON OF INTRA VAGINAL MISOPROSTOL WITH LOW- DOSE OXYTOCIN FOR CERVICAL RIPENING,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 10, no. 1, pp. 1–8, 2007, [Online]. Available: https://sid.ir/paper/64600/en

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