COMPARISON OF THE PERCENTAGE OF MEDICAL SUCCESS FOR PHYTOVAGEX VAGINAL SUPPOSITORY AND METRONIDAZOLE ORAL TABLET IN WOMEN WITH BACTERIAL VAGINOSIS

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JAFARNEZHAD FARZANEH; KIYANI MASK MAHIN; RAKHSHANDEH HASAN; SHAKERI MOHAMMAD TAGHI

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2017 | Volume:20 | Issue:3 Page(s): 29-39

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Title

COMPARISON OF THE PERCENTAGE OF MEDICAL SUCCESS FOR PHYTOVAGEX VAGINAL SUPPOSITORY AND METRONIDAZOLE ORAL TABLET IN WOMEN WITH BACTERIAL VAGINOSIS

Author(s)

JAFARNEZHAD FARZANEH | KIYANI MASK MAHIN | RAKHSHANDEH HASAN | SHAKERI MOHAMMAD TAGHI | Issue Writer Certificate

Keywords

BACTERIAL VAGINOSISQ1

PHYTOVAGEXQ1

METRONIDAZOLEQ2

NIGELLA SATIVAQ1

REMEDIAL SUCCESSQ2

Abstract

Introduction: BACTERIAL VAGINOSIS is the most common cause of vaginitis that itself is responsible for 50% of all cases of vaginitis.Metronidazole is considered the first line for treatment, but it is reported that there is carcinogen and resistance to METRONIDAZOLE. With regard to anti-bacterial effects of medicinal herbs such as NIGELLA SATIVA (the trade name of PHYTOVAGEX) on microbic organism, this study was done with aim to compare the REMEDIAL SUCCESS percentage of PHYTOVAGEX vaginal suppository with METRONIDAZOLE oral tablet in women with BACTERIAL VAGINOSIS.Methods: This triple-blind randomized clinical trial was done on 57 women with BACTERIAL VAGINOSIS referred to health centers subclass of health center No 2 in Mashhad at 2015-2016. The research units were randomly divided into intervention and control groups. The intervention group received PHYTOVAGEX vaginal suppository 1% once a day and placebo tablet twice a day for seven days, and control group received METRONIDAZOLE tablet 250 mg twice a day and placebo vaginal suppository once a day for seven days.7-10 days after treatment, the success percentage of treatment was investigated at each group by clinical standards. Data was analyzed by SPSS software (version 16) and independent t-test, Chi-square, Macnemar and Exact Fisher tests. P<0.05 was considered significant.Results: The success percentage of treatment of BACTERIAL VAGINOSIS was 74.2% in PHYTOVAGEX vaginal suppository group and 69.2% in METRONIDAZOLE tablet group that was not statistically significant (P>0.05).Conclusions: PHYTOVAGEX vaginal suppository is as effective as METRONIDAZOLE tablet in treatment of BACTERIAL VAGINOSIS and can be an appropriate alternative to treat BACTERIAL VAGINOSIS.

Cites

Za0Using the PCR method for detection of bacterial vaginosis in women suspected of vaginosis in Guilan province

References

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APA: Copy

JAFARNEZHAD, FARZANEH, KIYANI MASK, MAHIN, RAKHSHANDEH, HASAN, & SHAKERI, MOHAMMAD TAGHI. (2017). COMPARISON OF THE PERCENTAGE OF MEDICAL SUCCESS FOR PHYTOVAGEX VAGINAL SUPPOSITORY AND METRONIDAZOLE ORAL TABLET IN WOMEN WITH BACTERIAL VAGINOSIS. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 20(3), 29-39. SID. https://sid.ir/paper/64646/en

Vancouver: Copy

JAFARNEZHAD FARZANEH, KIYANI MASK MAHIN, RAKHSHANDEH HASAN, SHAKERI MOHAMMAD TAGHI. COMPARISON OF THE PERCENTAGE OF MEDICAL SUCCESS FOR PHYTOVAGEX VAGINAL SUPPOSITORY AND METRONIDAZOLE ORAL TABLET IN WOMEN WITH BACTERIAL VAGINOSIS. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2017;20(3):29-39. Available from: https://sid.ir/paper/64646/en

IEEE: Copy

FARZANEH JAFARNEZHAD, MAHIN KIYANI MASK, HASAN RAKHSHANDEH, and MOHAMMAD TAGHI SHAKERI, “COMPARISON OF THE PERCENTAGE OF MEDICAL SUCCESS FOR PHYTOVAGEX VAGINAL SUPPOSITORY AND METRONIDAZOLE ORAL TABLET IN WOMEN WITH BACTERIAL VAGINOSIS,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 20, no. 3, pp. 29–39, 2017, [Online]. Available: https://sid.ir/paper/64646/en

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