SHORT COMMUNICATION: PEDIATRIC GERM CELL TUMORS; A 10-YEAR EXPERIENCE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHALEGHNEJAD TABARI AHMAD; MIRSHEMIRANI ALIREZA; ROUZROKH MOHSEN; MOHAJERZADEH LEILY; KHALEGHNEJAD TABARI NASIBEH; HASAS YEGANEH SHAGHAYEGH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pediatrics Year:2014 | Volume:24 | Issue:4 Page(s): 441-444

Download Full-Text

View:

260

Download:

166

Cites:

Information Journal Paper

Title

SHORT COMMUNICATION: PEDIATRIC GERM CELL TUMORS; A 10-YEAR EXPERIENCE

Author(s)

Keywords

GERM CELL TUMOR

YOLK SAC TUMOR

TERATOMA

MALIGNANT TUMOR

Abstract

Objective: The aim of this study was to evaluate the outcome of GERM CELL TUMORs in patients admitted to our center during a ten year period.Methods: In a retrospective descriptive study, patients with the pathological diagnosis of GERM CELL TUMOR (GCT) were included. All records were evaluated and patients followed by personal visit in clinic or phone call. Data regarding age, sex, tumor site, bio-chemical assay, pathology, treatment and outcomes were gathered. For qualitative variables we computed frequency and percentage and for quantitative variables, mean and standard deviation. Survival analysis was performed using Kaplan-Meier. All statistical analyses were performed by SPSS version16.0.Findings: Forty four patients consisted of 32 girls (72.7%) and 12 boys (27.3%). Their median age was 23 months. The most common pathological tumor types were 18 (40.9%) mature TERATOMAs and 14 (31.8%) YOLK SAC TUMORs. Extra gonadal tumors were more prevalent (32 cases) and consisted of 21 (47.7%) sacrcoccygeal, 7 (15.9%) retroperitoneal, 2 (4.4%) mediastinal and 2 (4.4%) cervical tumors. In gonadal tumors 9 patients had ovarian and 3 patients testicular involvement. Staging at the time of diagnosis revealed stage one in 23 (52.3%) cases. All patients were treated surgically and the most common procedure was total resection in 41 (93.2%) patients. Fifteen (34.1%) patients received chemotherapy. In follow-up 31 (77.5%) patients were in complete remission, 9 (22.5%) had died, and 4 cases did not appear to follow-up visits. The median survival was 16 months (IQR 4-49 months). The highest mortality rate was found in patients with YOLK SAC TUMORs (8 of 13 cases).Conclusion: The patients with extra-gonadal GCT and a high AFP level have the worst prognosis and lower survival rate. Combination of surgery and chemotherapy can lead to a better prognosis.

Cites

No record.

References

No record.

Cite

APA: Copy

KHALEGHNEJAD TABARI, AHMAD, MIRSHEMIRANI, ALIREZA, ROUZROKH, MOHSEN, MOHAJERZADEH, LEILY, KHALEGHNEJAD TABARI, NASIBEH, & HASAS YEGANEH, SHAGHAYEGH. (2014). SHORT COMMUNICATION: PEDIATRIC GERM CELL TUMORS; A 10-YEAR EXPERIENCE. IRANIAN JOURNAL OF PEDIATRICS, 24(4), 441-444. SID. https://sid.ir/paper/647061/en

Vancouver: Copy

KHALEGHNEJAD TABARI AHMAD, MIRSHEMIRANI ALIREZA, ROUZROKH MOHSEN, MOHAJERZADEH LEILY, KHALEGHNEJAD TABARI NASIBEH, HASAS YEGANEH SHAGHAYEGH. SHORT COMMUNICATION: PEDIATRIC GERM CELL TUMORS; A 10-YEAR EXPERIENCE. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2014;24(4):441-444. Available from: https://sid.ir/paper/647061/en

IEEE: Copy

AHMAD KHALEGHNEJAD TABARI, ALIREZA MIRSHEMIRANI, MOHSEN ROUZROKH, LEILY MOHAJERZADEH, NASIBEH KHALEGHNEJAD TABARI, and SHAGHAYEGH HASAS YEGANEH, “SHORT COMMUNICATION: PEDIATRIC GERM CELL TUMORS; A 10-YEAR EXPERIENCE,” IRANIAN JOURNAL OF PEDIATRICS, vol. 24, no. 4, pp. 441–444, 2014, [Online]. Available: https://sid.ir/paper/647061/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops