RELATIONSHIP BETWEEN ASYMTOMATIC BRUCELLA INFECTION AND SPONTANEOUS ABORTION

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NASAJI ZAVAREH M.; RAHBAR NAHID; GHORBANI RAHEB; LAVAF S.

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2008 | Volume:11 | Issue:1 Page(s): 31-37

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Title

RELATIONSHIP BETWEEN ASYMTOMATIC BRUCELLA INFECTION AND SPONTANEOUS ABORTION

Author(s)

NASAJI ZAVAREH M. | RAHBAR NAHID | GHORBANI RAHEB | LAVAF S. | Issue Writer Certificate

Keywords

BRUCELLOSISQ3

SPONTANEOUS ABORTIONQ3

SEROLOGYQ4

PREGNANCYQ2

Abstract

Introduction: Brucella infection in animals has got documented association with high incidence of abortion, but in human there are controversies about the role of BRUCELLOSIS in SPONTANEOUS ABORTION. Since BRUCELLOSIS is endemic in Iran and is a disease that can be diagnosed and treated and many causes of abortion are undiagnosed, this study was designed to evaluate probable association between maternal brucella infection and SPONTANEOUS ABORTION.Materials and Methods: This clinical-trial study was done in the year 2006 at Amir-al Momenin Hospital of Semnan University of Medical Sciences. 81 women with SPONTANEOUS ABORTION were considered as case and 103 women with normal PREGNANCY outcome as control group. Previous PREGNANCY rates, previous abortion rates, and PREGNANCY age were similar in both groups. Two milliliter blood samples obtained from each one and IgG and IgM antibody measured by ELISA method in both groups. IgG or IgM equal or greater than ten considered positive. Individual, PREGNANCY age, fresh cheese and milk consumption, blood examination tests were gathered in a questionnaire and analyzed by descriptive statistics and statistical tests with significance of 5%.Results: Both groups were matched based on age, number of previous pregnancies and abortion, PREGNANCY age and consumption of fresh cheese. 6.2% of cases and 13.6% of control group had positive IgG titer (IgG³ 10 units). In both groups IgM was negative (IgM<10 units). There was no significant relationship between brucella antibody and SPONTANEOUS ABORTION. There was significant relationship between raw milk consumption and SPONTANEOUS ABORTION (OR=6.31).Conclusion: This study showed that asymptomatic brucella infection has no role in SPONTANEOUS ABORTION.

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APA: Copy

NASAJI ZAVAREH, M., RAHBAR, NAHID, GHORBANI, RAHEB, & LAVAF, S.. (2008). RELATIONSHIP BETWEEN ASYMTOMATIC BRUCELLA INFECTION AND SPONTANEOUS ABORTION. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 11(1), 31-37. SID. https://sid.ir/paper/64778/en

Vancouver: Copy

NASAJI ZAVAREH M., RAHBAR NAHID, GHORBANI RAHEB, LAVAF S.. RELATIONSHIP BETWEEN ASYMTOMATIC BRUCELLA INFECTION AND SPONTANEOUS ABORTION. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2008;11(1):31-37. Available from: https://sid.ir/paper/64778/en

IEEE: Copy

M. NASAJI ZAVAREH, NAHID RAHBAR, RAHEB GHORBANI, and S. LAVAF, “RELATIONSHIP BETWEEN ASYMTOMATIC BRUCELLA INFECTION AND SPONTANEOUS ABORTION,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 11, no. 1, pp. 31–37, 2008, [Online]. Available: https://sid.ir/paper/64778/en

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