THE ANALGESIC EFFECTS OF GABAPENTIN AFTER TOTAL ABDOMINAL HYSTERECTOMY

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MANSOUR GHANAEE MANDANA; MIRBLOOK FARIBA; BOINI SOHEILA; ERFANI SAYYAR REZA; SHAKIBA MARYAM; NAGHDI POUR MISA; RAHMANI SHAGHAYEGH

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2012 | Volume:15 | Issue:1 Page(s): 18-24

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Title

THE ANALGESIC EFFECTS OF GABAPENTIN AFTER TOTAL ABDOMINAL HYSTERECTOMY

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Keywords

ABDOMINAL HYSTERECTOMYQ2

GABAPANTINQ2

POSTOPERATIVE PAINQ2

Abstract

Introduction: POSTOPERATIVE PAIN is a major problem in general surgery which can severely effect on patient. Studies have shown that GABAPANTIN can produce analgesia and reduce the need for opioids in postoperative patients. In this study the efficacy of GABAPANTIN were studied as a premedication for reduce pain and need for opioids in ABDOMINAL HYSTERECTOMY.Methods: This double-blind clinical trial was performed in Alzahra maternity of Rasht in 2011.60 patients who undergo elective ABDOMINAL HYSTERECTOMY randomly were divided into GABAPANTIN group (1200mg) and placebo group (capsule like GABAPANTIN). Patients visited immediately after recovery and on second and forth hours after surgery in recovery room and VAS was recorded. Data were analyzed with SPSS version 16 by t-student and Mann-Whitney tests.Results: Age and surgery duration were matched in both groups. VAS was significantly difference in two groups for each of 3 visiting times (p=0.0001). Also the need for petidine was significantly more in control group than case group (p=0.0001).Conclusion: Administration of GABAPANTIN can reduce POSTOPERATIVE PAIN and improve sedation after surgery. GABAPANTIN as a premedication can also reduce need for opioids prescription.

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APA: Copy

MANSOUR GHANAEE, MANDANA, MIRBLOOK, FARIBA, BOINI, SOHEILA, ERFANI SAYYAR, REZA, SHAKIBA, MARYAM, NAGHDI POUR, MISA, & RAHMANI, SHAGHAYEGH. (2012). THE ANALGESIC EFFECTS OF GABAPENTIN AFTER TOTAL ABDOMINAL HYSTERECTOMY. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 15(1), 18-24. SID. https://sid.ir/paper/64884/en

Vancouver: Copy

MANSOUR GHANAEE MANDANA, MIRBLOOK FARIBA, BOINI SOHEILA, ERFANI SAYYAR REZA, SHAKIBA MARYAM, NAGHDI POUR MISA, RAHMANI SHAGHAYEGH. THE ANALGESIC EFFECTS OF GABAPENTIN AFTER TOTAL ABDOMINAL HYSTERECTOMY. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2012;15(1):18-24. Available from: https://sid.ir/paper/64884/en

IEEE: Copy

MANDANA MANSOUR GHANAEE, FARIBA MIRBLOOK, SOHEILA BOINI, REZA ERFANI SAYYAR, MARYAM SHAKIBA, MISA NAGHDI POUR, and SHAGHAYEGH RAHMANI, “THE ANALGESIC EFFECTS OF GABAPENTIN AFTER TOTAL ABDOMINAL HYSTERECTOMY,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 15, no. 1, pp. 18–24, 2012, [Online]. Available: https://sid.ir/paper/64884/en

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