COMPARISON OF MEFENAMIC ACID, AND TRANEXAMIC ACID IN TREATMENT OF HYPERMENORRHEA

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SEKHAVAT L.; ZARE TAZARJANI F.; KARIMZADEH MEYBODI M.A.

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2007 | Volume:9 | Issue:2 Page(s): 17-22

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Title

COMPARISON OF MEFENAMIC ACID, AND TRANEXAMIC ACID IN TREATMENT OF HYPERMENORRHEA

Author(s)

SEKHAVAT L. | ZARE TAZARJANI F. | KARIMZADEH MEYBODI M.A. | Issue Writer Certificate

Keywords

HYPER MENORRHEAQ4

TRANEXAMIC ACIDQ3

MEFENAMIC ACIDQ2

Abstract

Introduction: Excessive menstrual bleeding is a common complaint and each year around 5% of 30-49 year old women have this problem. The aim of this study is to compare the efficacy and acceptability of MEFENAMIC ACID and TRANEXAMIC ACID for treating menorrhea. Attempts have been made to choose a more effective with less complication to treat HYPER MENORRHEA.Materials and Methods: This study is a control trial study and the setting is Shahid Sedugh University, department of obstetrics and gynecology, Yazd in 2001-2005. 75 women with excessive uterine bleeding (HYPER MENORRHEA) were under treatment for five days from day 1 of menses during three consecutive menstrual periods. 36 patients were randomized to take MEFENAMIC ACID 500 mg, Tid; and 39 patients to take 500 mg TRANEXAMIC ACID, Qid.Menstrual loss was measured in three control menstrual periods and three menstrual periods during treatment. Duration of bleeding patient's estimated blood loss, sanitary towel usage and unwanted events were also taken into consideration.Results: MEFENAMIC ACID reduced blood loss by 20% and TRANEXAMIC ACID reduced blood loss by 50% (P=0.001). Duration of bleeding was not different in patients treated with MEFENAMIC ACID and TRANEXAMIC ACID.Conclusions: TRANEXAMIC ACID given during menstruation is a safe and highly effective treatment for excessive bleeding. Patients with dysfunctional uterine bleeding should be offered medical treatment with TRANEXAMIC ACID before a decision is made about surgery.

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APA: Copy

SEKHAVAT, L., ZARE TAZARJANI, F., & KARIMZADEH MEYBODI, M.A.. (2007). COMPARISON OF MEFENAMIC ACID, AND TRANEXAMIC ACID IN TREATMENT OF HYPERMENORRHEA. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 9(2), 17-22. SID. https://sid.ir/paper/65339/en

Vancouver: Copy

SEKHAVAT L., ZARE TAZARJANI F., KARIMZADEH MEYBODI M.A.. COMPARISON OF MEFENAMIC ACID, AND TRANEXAMIC ACID IN TREATMENT OF HYPERMENORRHEA. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2007;9(2):17-22. Available from: https://sid.ir/paper/65339/en

IEEE: Copy

L. SEKHAVAT, F. ZARE TAZARJANI, and M.A. KARIMZADEH MEYBODI, “COMPARISON OF MEFENAMIC ACID, AND TRANEXAMIC ACID IN TREATMENT OF HYPERMENORRHEA,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 9, no. 2, pp. 17–22, 2007, [Online]. Available: https://sid.ir/paper/65339/en

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