COMPARISON OF THE EFFECT OF ORAL MISOPROSTOL TABLET WITH INTRAVENOUS OXYTOCIN FOR PREGNANCY TERMINATION IN GYNECOLOGY WARDS OF ACADEMIC HOSPITALS IN MASHHAD (2003-2004)

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LOTF ALIZADEH M.; GHOMIAN N.

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2007 | Volume:9 | Issue:2 Page(s): 104-109

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Title

COMPARISON OF THE EFFECT OF ORAL MISOPROSTOL TABLET WITH INTRAVENOUS OXYTOCIN FOR PREGNANCY TERMINATION IN GYNECOLOGY WARDS OF ACADEMIC HOSPITALS IN MASHHAD (2003-2004)

Author(s)

LOTF ALIZADEH M. | GHOMIAN N. | Issue Writer Certificate

Keywords

MISOPROSTOLQ3

SECOND TRIMESTER OF PREGNANCYQ3

OXYTOCINQ3

TERMINATION OF PREGNANCYQ4

Abstract

Introduction: Since most of cases of pregnancy termination are induced by OXYTOCIN of which needs special care, much time, costs, and it has side effects such as water toxicity especially in prolonged inductions trying to find suitable replacement for OXYTOCIN is necessary. The aim of this research is compared on OXYTOCIN with MISOPROSTOL in the SECOND TRIMESTER OF PREGNANCY gynecology ward of academic hospitals in Mashhad. (Imam Reza – Ghaem – Hazrat Zeinab)Materials and Methods: In this prospective case – control study, we divided 125 pregnant women in the second trimester to two groups. Pregnancy termination in the case group was induced by administration 3 100μg oral tablets of MISOPROSTOL and one vaginal MISOPROSTOL tablet.If there wasn’t any uterine contraction we used one oral tablet every 3 hours and a vaginal tablet every 4 –6 hours for 48 hours.In the control group pregnancy termination was induced by OXYTOCIN. 50I/U of OXYTOCIN was diluted with 500CC Ringer and infused in 3 hours then there was a resting period for l hour and then we increase 50I/U OXYTOCIN in 500CC Ringer until maximum 300I/U in 500 CC Ringer. Our plan was 3 hours of induction and an hour resting until beginning of contraction or no responding after 48 hours induction.Another method of delivery induction was replaced, if no contraction was observed after 48 hours in both groups.Results: Labor contraction and pregnancy termination happened sooner in the MISOPROSTOL group than OXYTOCIN group. (p=0.001) Placental retention and costs were less in the case group (p<0.05). Fever, bleeding, gastrointestinal tract complications and uterine rupture had no difference in both groups. (p>0.05)Conclusion: Misoprastol alone induced delivery sooner when was compared to OXYTOCIN, in the second trimester and it also had less cost and less side effects. Besides it dose not need intensive nurse care. So we recommend MISOPROSTOL for pregnancy termination in the second trimester.

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APA: Copy

LOTF ALIZADEH, M., & GHOMIAN, N.. (2007). COMPARISON OF THE EFFECT OF ORAL MISOPROSTOL TABLET WITH INTRAVENOUS OXYTOCIN FOR PREGNANCY TERMINATION IN GYNECOLOGY WARDS OF ACADEMIC HOSPITALS IN MASHHAD (2003-2004). IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 9(2), 104-109. SID. https://sid.ir/paper/65340/en

Vancouver: Copy

LOTF ALIZADEH M., GHOMIAN N.. COMPARISON OF THE EFFECT OF ORAL MISOPROSTOL TABLET WITH INTRAVENOUS OXYTOCIN FOR PREGNANCY TERMINATION IN GYNECOLOGY WARDS OF ACADEMIC HOSPITALS IN MASHHAD (2003-2004). IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2007;9(2):104-109. Available from: https://sid.ir/paper/65340/en

IEEE: Copy

M. LOTF ALIZADEH, and N. GHOMIAN, “COMPARISON OF THE EFFECT OF ORAL MISOPROSTOL TABLET WITH INTRAVENOUS OXYTOCIN FOR PREGNANCY TERMINATION IN GYNECOLOGY WARDS OF ACADEMIC HOSPITALS IN MASHHAD (2003-2004),” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 9, no. 2, pp. 104–109, 2007, [Online]. Available: https://sid.ir/paper/65340/en

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