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Information Journal Paper

Title

RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) OF 131I RADIATION RELATIVE TO 60CO GAMMA RAYS

Pages

  224-229

Abstract

 Objective: To assess relative biological effectiveness (RBE) of 131I radiation relative to 60Co gamma rays in GLIOBLASTOMA SPHEROID cells. Materials and Methods: In this experimental study, GLIOBLASTOMA SPHEROID cells were exposed to 131I radiation and 60Co gamma rays. Radiation induced DNA damage was evaluated by alkaline comet assay. Samples of SPHEROID cells were treated by radiation from 131I for four different periods of time to find the dose-response equation. SPHEROID cells were also exposed by 200 cGy of 60Co gamma rays as reference radiation to induce DNA damage as endpoint. Results: Resulted RBE of 131I radiation relative to 60Co gamma rays in 100mm giloblas-toma SPHEROID cells was equal to 1.16.Conclusion: The finding of this study suggests that 131I PHOTONS and ELECTRONS can be more effective than 60Co gamma rays to produce DNA damage in GLIOBLASTOMA SPHEROID cells.

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    Cite

    APA: Copy

    NESHASTEH RIZ, ALI, PASHAZADEH, ALI MAHMOUD, & MAHDAVI, SEYED RABIE. (2013). RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) OF 131I RADIATION RELATIVE TO 60CO GAMMA RAYS. CELL JOURNAL (YAKHTEH), 15(3 (59)), 224-229. SID. https://sid.ir/paper/654665/en

    Vancouver: Copy

    NESHASTEH RIZ ALI, PASHAZADEH ALI MAHMOUD, MAHDAVI SEYED RABIE. RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) OF 131I RADIATION RELATIVE TO 60CO GAMMA RAYS. CELL JOURNAL (YAKHTEH)[Internet]. 2013;15(3 (59)):224-229. Available from: https://sid.ir/paper/654665/en

    IEEE: Copy

    ALI NESHASTEH RIZ, ALI MAHMOUD PASHAZADEH, and SEYED RABIE MAHDAVI, “RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) OF 131I RADIATION RELATIVE TO 60CO GAMMA RAYS,” CELL JOURNAL (YAKHTEH), vol. 15, no. 3 (59), pp. 224–229, 2013, [Online]. Available: https://sid.ir/paper/654665/en

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