ANALYSIS OF OUTCOME OF INTRAPLUERAL STREPTOKINASE IN PEDIATRIC EMPYEMA THORACIS EVEN IN ADVANCED STAGES: A PROSPECTIVE STUDY

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BOSE KALLOL; SAHA SUDIP; MRIDHA DHRUBOJYOTI; DAS KALLOL; MONDAL PIYASI; DAS IRA

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Journal: Iranian Journal of Pediatrics Year:2015 | Volume:25 | Issue:5 Page(s): 0-0

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Title

ANALYSIS OF OUTCOME OF INTRAPLUERAL STREPTOKINASE IN PEDIATRIC EMPYEMA THORACIS EVEN IN ADVANCED STAGES: A PROSPECTIVE STUDY

Author(s)

Keywords

EMPYEMA THORACIS

PEDIATRICS

STREPTOKINASE

Abstract

Background: EMPYEMA THORACIS in children causes significant morbidity. Standard treatment of EMPYEMA THORACIS includes tube drainage and antibiotics. But the tube drainage often fails. Intrapleural STREPTOKINASE has been used in EMPYEMA THORACIS with good success rate.Objectives: We evaluated the efficacy of intra-pleural STREPTOKINASE in management of EMPYEMA THORACIS even in advanced stages.Patients and Methods: A total of 28 patients with EMPYEMA THORACIS requiring intercostal tube drainage aged zero to twelve years were included in the study who were admitted in Pediatric intensive care unit. 15,000 units/kg of STREPTOKINASE was instilled into the pleural cavity. Response was assessed by clinical outcome, after unclamping and subsequent chest radiography and serial chest ultrasounds.Results: STREPTOKINASE enhanced drainage in all patients with complete resolution of EMPYEMA THORACIS in 26 patients. Two patients were referred for surgery. Only 7.2% required surgery. STREPTOKINASE was equally effective if started before or after seven days.Conclusions: Intrapleural STREPTOKINASE is the preferred treatment for treating pediatric EMPYEMA THORACIS even in advanced stages and can avoid surgery.

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APA: Copy

BOSE, KALLOL, SAHA, SUDIP, MRIDHA, DHRUBOJYOTI, DAS, KALLOL, MONDAL, PIYASI, & DAS, IRA. (2015). ANALYSIS OF OUTCOME OF INTRAPLUERAL STREPTOKINASE IN PEDIATRIC EMPYEMA THORACIS EVEN IN ADVANCED STAGES: A PROSPECTIVE STUDY. IRANIAN JOURNAL OF PEDIATRICS, 25(5), 0-0. SID. https://sid.ir/paper/665745/en

Vancouver: Copy

BOSE KALLOL, SAHA SUDIP, MRIDHA DHRUBOJYOTI, DAS KALLOL, MONDAL PIYASI, DAS IRA. ANALYSIS OF OUTCOME OF INTRAPLUERAL STREPTOKINASE IN PEDIATRIC EMPYEMA THORACIS EVEN IN ADVANCED STAGES: A PROSPECTIVE STUDY. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2015;25(5):0-0. Available from: https://sid.ir/paper/665745/en

IEEE: Copy

KALLOL BOSE, SUDIP SAHA, DHRUBOJYOTI MRIDHA, KALLOL DAS, PIYASI MONDAL, and IRA DAS, “ANALYSIS OF OUTCOME OF INTRAPLUERAL STREPTOKINASE IN PEDIATRIC EMPYEMA THORACIS EVEN IN ADVANCED STAGES: A PROSPECTIVE STUDY,” IRANIAN JOURNAL OF PEDIATRICS, vol. 25, no. 5, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/665745/en

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