EFFICACY OF MORPHINE INJECTION VERSUS SUBLINGUAL BUPRENORPHINE IN POSTOPERATIVE PAIN AFTER LUMBAR LAMINECTOMY

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ABDOLHOSSEINPOUR HESAM; ARBABI AMIRHOSSEIN; MOSLEM ALIREZA; TAJIK ALI

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Journal: Internal Medicine Today Year:2010 | Volume:16 | Issue:3 (49) Page(s): 20-24

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Title

EFFICACY OF MORPHINE INJECTION VERSUS SUBLINGUAL BUPRENORPHINE IN POSTOPERATIVE PAIN AFTER LUMBAR LAMINECTOMY

Author(s)

ABDOLHOSSEINPOUR HESAM | ARBABI AMIRHOSSEIN | MOSLEM ALIREZA | TAJIK ALI | Issue Writer Certificate

Keywords

BUPRENORPHINEQ3

LAMINECTOMYQ3

MORPHINEQ2

POSTOPERATIVE PAINQ2

Abstract

Background and Aim: POSTOPERATIVE PAIN is a major consequent of lumbar LAMINECTOMY. Hence, this study was conducted to determine the efficacy of MORPHINE injection versus sublingual BUPRENORPHINE in POSTOPERATIVE PAIN after lumbar LAMINECTOMY in Booali Hospital in 2007-2008.Materials and Methods: This study was conducted as a single-blind randomized clinical trial. The patients (in two groups of 25 subjects) were randomly assigned to receive either 0.4 mg of sublingual BUPRENORPHINE or 10 mg of intravenous MORPHINE three times. The patients were monitored for POSTOPERATIVE PAIN in a period of 24 hours after surgery. The data were analyzed through SPSS software version.13 using t-test and chi-square.Results: Before intervention, VAS was 8±1.04 and 7.72±1.06 in MORPHINE and BUPRENORPHINE groups, respectively, a finding which was statistically insignificant (p>0.05). Within a period of 12 to 24 hours after intervention, visual analogue scale (VAS) was decreased 2.08±0.95 in MORPHINE group and 3.28±0.67 in BUPRENORPHINE group ([p=0.0001). Further, 24 hours after intervention, VAS was decreased 2.08±0.9 in MORPHINE group and 2.6±0.95 in BUPRENORPHINE group (p=0.055).Conclusion: Totally, it may be concluded that sublingual BUPRENORPHINE may be used as an easy and effective method for pain reduction after lumbar disc surgeries in comparison with intravenous MORPHINE.

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APA: Copy

ABDOLHOSSEINPOUR, HESAM, ARBABI, AMIRHOSSEIN, MOSLEM, ALIREZA, & TAJIK, ALI. (2010). EFFICACY OF MORPHINE INJECTION VERSUS SUBLINGUAL BUPRENORPHINE IN POSTOPERATIVE PAIN AFTER LUMBAR LAMINECTOMY. OFOGH-E-DANESH, 16(3 (49)), 20-24. SID. https://sid.ir/paper/68634/en

Vancouver: Copy

ABDOLHOSSEINPOUR HESAM, ARBABI AMIRHOSSEIN, MOSLEM ALIREZA, TAJIK ALI. EFFICACY OF MORPHINE INJECTION VERSUS SUBLINGUAL BUPRENORPHINE IN POSTOPERATIVE PAIN AFTER LUMBAR LAMINECTOMY. OFOGH-E-DANESH[Internet]. 2010;16(3 (49)):20-24. Available from: https://sid.ir/paper/68634/en

IEEE: Copy

HESAM ABDOLHOSSEINPOUR, AMIRHOSSEIN ARBABI, ALIREZA MOSLEM, and ALI TAJIK, “EFFICACY OF MORPHINE INJECTION VERSUS SUBLINGUAL BUPRENORPHINE IN POSTOPERATIVE PAIN AFTER LUMBAR LAMINECTOMY,” OFOGH-E-DANESH, vol. 16, no. 3 (49), pp. 20–24, 2010, [Online]. Available: https://sid.ir/paper/68634/en

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