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Information Journal Paper

Title

SURVEY OF THE EFFECT OF POWDER NIGELLA SATIVA (BLACK SEED) IN INCRESCENT OF MONOCYTE PHAGOCYTOSIS IN QUINEA PIG

Pages

  55-63

Abstract

 Background and Aim: In most infections and diseases, induction and increasing power of immuno system are necessary to cure and decrease the effect of the disease. NIGELLA SATIVA is a plant that has been used for treatment of many diseases. In this survey, the effect of NIGELLA SATIVA is surveyed in strengthening of Monocyte PHAGOCYTOSIS so that the use and mechanism of this plant for strengthening the PHAGOCYTOSIS of main cells of immune system are characterized.Materials and Methods: For this purpose, 21 male quinea pigs were selected and divided into three groups: control group given nothing, treatment group with taking %6.25 NIGELLA SATIVA nutrient and another treatment group with taking %12.5 NIGELLA SATIVA nutrient for 3 weeks. At an even period, blood samples were taken and peripheral blood mononuclear cells (PBMC) were separated from each subject's Heparin Blood in the Faikol-Hypak style. Finally, the three tests, that is, reduction Nitro Blue Tetrazolium (NBT) renewal, PHAGOCYTOSIS with yeast and latex bead floressance were given.Results: The results have shown that increasing of PHAGOCYTOSIS in Monocyte is meaningful (p£0.05).Conclusion: Using Black seed with food causes the increasing of PHAGOCYTOSIS in mononuclear cells and increasing of PHAGOCYTOSIS activity for uptake of foreign particles and pathogens. Thus, this substance can be used to define pathogens through activating Monocyte-Macrophage pathway, that is, the connector between the innate and adaptive immuno systems.

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    APA: Copy

    DELIREJH, NOWRUZ, MORSHEDI, AHMAD, & ATHARI, SEYYED SHAMSADIN. (2010). SURVEY OF THE EFFECT OF POWDER NIGELLA SATIVA (BLACK SEED) IN INCRESCENT OF MONOCYTE PHAGOCYTOSIS IN QUINEA PIG. OFOGH-E-DANESH, 16(3 (49)), 55-63. SID. https://sid.ir/paper/68635/en

    Vancouver: Copy

    DELIREJH NOWRUZ, MORSHEDI AHMAD, ATHARI SEYYED SHAMSADIN. SURVEY OF THE EFFECT OF POWDER NIGELLA SATIVA (BLACK SEED) IN INCRESCENT OF MONOCYTE PHAGOCYTOSIS IN QUINEA PIG. OFOGH-E-DANESH[Internet]. 2010;16(3 (49)):55-63. Available from: https://sid.ir/paper/68635/en

    IEEE: Copy

    NOWRUZ DELIREJH, AHMAD MORSHEDI, and SEYYED SHAMSADIN ATHARI, “SURVEY OF THE EFFECT OF POWDER NIGELLA SATIVA (BLACK SEED) IN INCRESCENT OF MONOCYTE PHAGOCYTOSIS IN QUINEA PIG,” OFOGH-E-DANESH, vol. 16, no. 3 (49), pp. 55–63, 2010, [Online]. Available: https://sid.ir/paper/68635/en

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