Effect of Iron on Thyroid Function in Women With Hypothyroidism: A Doubleblind Clinical Trial Study

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHIRAVAND ZAHRA; TALAEI AFSANEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Arak University Medical Sciences Year:2019 | Volume:22 | Issue:4 Page(s): 124-133

Download Full-Text

Persian Verion

View:

600

Download:

406

Cites:

Information Journal Paper

Title

Effect of Iron on Thyroid Function in Women With Hypothyroidism: A Doubleblind Clinical Trial Study

Author(s)

SHIRAVAND ZAHRA | TALAEI AFSANEH | Issue Writer Certificate

Keywords

HypothyroidismQ3

IronQ3

LevothyroxineQ3

Abstract

human experiences indicate that Iron deficiency disrupts thyroid metabolism. On the other hand, Iron therapy can improve thyroid function and even decrease the dose of Levothyroxine. Methods and Materials In this randomized clinical trial, we selected 94 women with Hypothyroidism by simple random sampling method and divided them into two equal groups by simple block sampling. At the beginning of the study, we measured and recorded T4, TSH, T3, and Iron profiles (Serum Iron, total Iron-binding capacity, ferritin, Hemoglobin) in all patients. Then, the patients in the intervention group were treated with Levothyroxine plus 100 mg oral Iron daily for 8 weeks, and the patients in the control group were treated with Levothyroxine only. After two months, we measured their T4, TSH, T3 levels and Iron profiles in both groups again. Ethical Considerations The Research Ethics Committee of Arak University of Medical Sciences approved this study (Research Ethics Code: 1396154). Also, the study has been registered at the Iranian Registry of Clinical Trials (Code: IRCT 20151114025031). Results After 2 months, the TSH Mean± SD serum levels were found as 2. 2± 1. 0 mIU/L and 2. 9± 1. 1 mIU/L for the intervention and control group, respectively (P=0. 04). Also, the serum Mean± SD level of T4 and T3 were found as 9. 3± 1. 48 mcg/dL vs. 8. 2± 0. 9 mcg/dL (P=0. 01), and 1. 6± 0. 3 ng/mL vs. 1. 1± 0. 3 ng/mL (P=0. 01), for two different groups, respectively. Conclusion Concurrent administration of Iron supplementation with the usual dose of Levothyroxine in patients with Hypothyroidism decreases THS level and improves laboratory parameters and response to treatment.

Cites

No record.

References

Thyroid function among children with iron deficiency anaemia: Pre and post iron replacement therapy

Cite

APA: Copy

SHIRAVAND, ZAHRA, & TALAEI, AFSANEH. (2019). Effect of Iron on Thyroid Function in Women With Hypothyroidism: A Doubleblind Clinical Trial Study. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 22(4 ), 124-133. SID. https://sid.ir/paper/68854/en

Vancouver: Copy

SHIRAVAND ZAHRA, TALAEI AFSANEH. Effect of Iron on Thyroid Function in Women With Hypothyroidism: A Doubleblind Clinical Trial Study. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2019;22(4 ):124-133. Available from: https://sid.ir/paper/68854/en

IEEE: Copy

ZAHRA SHIRAVAND, and AFSANEH TALAEI, “Effect of Iron on Thyroid Function in Women With Hypothyroidism: A Doubleblind Clinical Trial Study,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 22, no. 4 , pp. 124–133, 2019, [Online]. Available: https://sid.ir/paper/68854/en

Related Journal Papers