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Information Journal Paper

Title

BRIEF REPORT: FACTORS ASSOCIATED WITH CHANGES IN MAGNESIUM LEVELS IN ASYMPTOMATIC NEONATES: A LONGITUDINAL ANALYSIS

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Abstract

 Background: Neonates and infants with HYPOMAGNESEMIA present with seizures and psychomotor delay.Objectives: The present study evaluated the changes in MAGNESIUM (Mg) levels and factors associated with these in the first three days of life.Materials and Methods: We monitored 50 clinically asymptomatic neonates; they were not given any MAGNESIUM supplements even if they had HYPOMAGNESEMIA at baseline. The variables analysed were: serum Mg; gestational age; birth weight; length; and the ponderal index. We used random effects (RE) models for longitudinal analysis of these data.Results: The mean standard deviation (SD) gestational age was 36.3 (3.6) weeks and the mean (SD) weight was 2604.2 (754.4) grams. About 31% of the neonates had HYPOMAGNESEMIA (<1.6 mg/dL) on day one; however, all had normal MAGNESIUM levels by day three of life (P<0.001). At birth, after adjusting for intrauterine growth retardation status (IUGR), serum Mg levels were lower by 0.0097 mg/dL (95% CI: -0.019 to -0.0003) per 100 grams increase in weight of the neonate. After adjusting for IUGR status, the mean increase in the serum Mg levels was 0.14 mg/dL (95% confidence intervals [CI]: 0.10 to 0.18) per day. The per-day increase in MAGNESIUM levels was significantly higher in low birth weight babies (0.10, 95% CI: 0.01 to 0.18) compared with normal birth weight babies.Conclusions: Asymptomatic neonates may have a high prevalence of HYPOMAGNESEMIA; however, the levels become normal without any MAGNESIUM SUPPLEMENTATION. Even though regular monitoring of MAGNESIUM levels is useful, no supplements are required - particularly in clinically asymptomatic neonates.

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    APA: Copy

    MEHTA, YOGESH, SHITOLE, CHARUDATTA, & SETIA, MANINDER SINGH. (2016). BRIEF REPORT: FACTORS ASSOCIATED WITH CHANGES IN MAGNESIUM LEVELS IN ASYMPTOMATIC NEONATES: A LONGITUDINAL ANALYSIS. IRANIAN JOURNAL OF PEDIATRICS, 26(1), 0-0. SID. https://sid.ir/paper/689296/en

    Vancouver: Copy

    MEHTA YOGESH, SHITOLE CHARUDATTA, SETIA MANINDER SINGH. BRIEF REPORT: FACTORS ASSOCIATED WITH CHANGES IN MAGNESIUM LEVELS IN ASYMPTOMATIC NEONATES: A LONGITUDINAL ANALYSIS. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2016;26(1):0-0. Available from: https://sid.ir/paper/689296/en

    IEEE: Copy

    YOGESH MEHTA, CHARUDATTA SHITOLE, and MANINDER SINGH SETIA, “BRIEF REPORT: FACTORS ASSOCIATED WITH CHANGES IN MAGNESIUM LEVELS IN ASYMPTOMATIC NEONATES: A LONGITUDINAL ANALYSIS,” IRANIAN JOURNAL OF PEDIATRICS, vol. 26, no. 1, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/689296/en

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