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Information Journal Paper

Title

THE EFFECT OF THREE-WEEK INTENSIVE INTERVAL TRAINING ON LIPOCALIN-2 AND INTERLEUKIN1-β IN HEALTHY AND ADULT RAT HIPPOCAMPUS

Author(s)

HASANVAND BAHMAN | SOORI RAHMAN | ABBASIAN SADEGH | RASTEGAR MOGHADDAM MANSOORI MAHSA | Issue Writer Certificate 

Pages

  24-34

Abstract

 Background: In response to the exercise, variety of inflammatory and anti- inflammatory changes in cytokines were occurred into the tissue spaces and also to the systemic circulation. The purpose of  the current study was to determine the effect of three-week INTENSIVE INTERVAL TRAINING on LIPOCALIN-2 and Interleukin1- b in healthy and adult rat hippocampus.Materials and Methods: Twenty Wistar rats were divided into training and control groups. Training group performed 15 (bouts)×4 (min) exercise training for 60 min with 85 to 90% of VO2max used for four sessions/week (for 3 weeks). Then, blood (for ELISA analyzing) and tissue sampling was performed from rat’s hippocampus and they were evaluated by using a Real-Time PCR method. Also, independent and paired t tests were used to define within and between group differences.Results: Findings showed that gene translations of LIPOCALIN-2 and Interleukin1-b were significantly decreased in rat’s hippocampus (p=0.0001 and p=0.0001, respectively). Also, similar decreases were shown in serum levels of LIPOCALIN-2 and Interleukin1-b in rats (p=0.017 and p=0.003, respectively).Conclusion: It seems that significant decrease of LIPOCALIN-2 subsequent of short-time INTENSIVE INTERVAL TRAINING is due to decreasing and significant changes in Interleukin1-b. Also, current training protocol on treadmill can significantly decrease levels of LIPOCALIN-2 and Interleukin1-b in rat serum and hippocampus.

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    Cite

    APA: Copy

    HASANVAND, BAHMAN, SOORI, RAHMAN, ABBASIAN, SADEGH, & RASTEGAR MOGHADDAM MANSOORI, MAHSA. (2017). THE EFFECT OF THREE-WEEK INTENSIVE INTERVAL TRAINING ON LIPOCALIN-2 AND INTERLEUKIN1-β IN HEALTHY AND ADULT RAT HIPPOCAMPUS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 20(1 (118)), 24-34. SID. https://sid.ir/paper/69146/en

    Vancouver: Copy

    HASANVAND BAHMAN, SOORI RAHMAN, ABBASIAN SADEGH, RASTEGAR MOGHADDAM MANSOORI MAHSA. THE EFFECT OF THREE-WEEK INTENSIVE INTERVAL TRAINING ON LIPOCALIN-2 AND INTERLEUKIN1-β IN HEALTHY AND ADULT RAT HIPPOCAMPUS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2017;20(1 (118)):24-34. Available from: https://sid.ir/paper/69146/en

    IEEE: Copy

    BAHMAN HASANVAND, RAHMAN SOORI, SADEGH ABBASIAN, and MAHSA RASTEGAR MOGHADDAM MANSOORI, “THE EFFECT OF THREE-WEEK INTENSIVE INTERVAL TRAINING ON LIPOCALIN-2 AND INTERLEUKIN1-β IN HEALTHY AND ADULT RAT HIPPOCAMPUS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 20, no. 1 (118), pp. 24–34, 2017, [Online]. Available: https://sid.ir/paper/69146/en

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