THE EFFECT OF BERBERINE ON PATIENTS WITH PSORIASIS

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GHORBANI BIRGANI A.; ABEDI P.; ZARE K.; ASADPOOR S.

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Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2013 | Volume:15 | Issue:15 (67) Page(s): 0-0

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Title

THE EFFECT OF BERBERINE ON PATIENTS WITH PSORIASIS

Author(s)

GHORBANI BIRGANI A. | ABEDI P. | ZARE K. | ASADPOOR S. | Issue Writer Certificate

Keywords

BERBERINEQ2

PSORIASISQ3

PASIQ2

Abstract

Background: PSORIASIS is a common chronic skin disease which usually appears as white and silvery spots on the skin. The purpose of this study is to investigate the effect of BERBERINE on patients with PSORIASIS.Materials and Methods: This double-blind clinical trial was conducted on 60 PSORIASIS patients who referred to Imam Khomeini Hospital, Ahvoaz, between July and December 2011. The patients were randomly divided into two equal groups that applied BERBERINE and placebo to the treatment of their lesions twice a day. Lesions severity rate in the patients was assessed 7 times using a PSORIASIS Area Severity Index (PASI). Data were analyzed by ANOVA with repeated measurements and Chi-square using SPSS software. Results: After 6 months, severity of lesions showed a significant decrease in the group receiving the BERBERINE cream compared with the placebo group so that the mean PASI score of the group receiving BERBERINE decreased from 3.99 to 2.11 while in the placebo group this decreased from 3.98 to 3.71. Mean difference in PASI score was not significant before receiving the treatment till the third month in BERBERINE and placebo groups, but in the fourth to sixth months it was statistically significant (p=0.013).Conclusion: BERBERINE cream was more effective than the placebo in reduction of skin lesions of PSORIASIS patients. Therefore, it is recommended that plant-based drugs, like BERBERINE, be used more besides the main medications of patients.

Cites

THE LIVED EXPERIENCE OF PSORIASIS PATIENTS FROM SOCIAL STIGMA AND REJECTION: A QUALITATIVE STUDY

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APA: Copy

GHORBANI BIRGANI, A., ABEDI, P., ZARE, K., & ASADPOOR, S.. (2013). THE EFFECT OF BERBERINE ON PATIENTS WITH PSORIASIS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 15(15 (67)), 0-0. SID. https://sid.ir/paper/69189/en

Vancouver: Copy

GHORBANI BIRGANI A., ABEDI P., ZARE K., ASADPOOR S.. THE EFFECT OF BERBERINE ON PATIENTS WITH PSORIASIS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2013;15(15 (67)):0-0. Available from: https://sid.ir/paper/69189/en

IEEE: Copy

A. GHORBANI BIRGANI, P. ABEDI, K. ZARE, and S. ASADPOOR, “THE EFFECT OF BERBERINE ON PATIENTS WITH PSORIASIS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 15, no. 15 (67), pp. 0–0, 2013, [Online]. Available: https://sid.ir/paper/69189/en

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