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Information Journal Paper

Title

Study the Association Between CPEB2 Gene Polymorphism with the Risk of Idiopathic Azoospermia/Severe Oligozoospermia of Men

Pages

  88-98

Abstract

 Background and Aim: The CPEB gene encodes an important protein, which play critical roles in translational regulation of oogenesis and spermatogenesis procedures. The aim of this study was to evaluate the association between CPEB2 rs12643066 gene polymorphism with the risk of idiopathic Azoospermia/severe Oligozoospermia of men. Materials and Methods: This study was designed as a case-control investigation on 100 blood samples of men with idiopathic Azoospermia/severe Oligozoospermia and 100 blood samples of fertile men. To evaluate CPEB2 gene polymorphism, PCR-RFLP method was used. Data analysis was performed by chi-squat test. Findings: In the present study, the genotype frequencies did not show a statically significant difference between groups (p=0. 479, OR=1. 222; CI=0. 701-2. 129). Conclusion: The study showed that the CPEB2 gene polymorphism was not associated with the risk of idiopathic Azoospermia/severe Oligozoospermia of men. However, it is conceivable that evaluation of this gene polymorphism can not be used as a biomarker in diagnosis of men with idiopathic Azoospermia/severe Oligozoospermia.

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    APA: Copy

    KIAN Bostanabad, Reza, & GHORBIAN, SAEID. (2018). Study the Association Between CPEB2 Gene Polymorphism with the Risk of Idiopathic Azoospermia/Severe Oligozoospermia of Men. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 21(6 (135) ), 88-98. SID. https://sid.ir/paper/69316/en

    Vancouver: Copy

    KIAN Bostanabad Reza, GHORBIAN SAEID. Study the Association Between CPEB2 Gene Polymorphism with the Risk of Idiopathic Azoospermia/Severe Oligozoospermia of Men. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2018;21(6 (135) ):88-98. Available from: https://sid.ir/paper/69316/en

    IEEE: Copy

    Reza KIAN Bostanabad, and SAEID GHORBIAN, “Study the Association Between CPEB2 Gene Polymorphism with the Risk of Idiopathic Azoospermia/Severe Oligozoospermia of Men,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 21, no. 6 (135) , pp. 88–98, 2018, [Online]. Available: https://sid.ir/paper/69316/en

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