DETERMINATION OF CHROMOSOMAL CHANGES IN DMBA-INDUCED SKIN CANCER IN SD RAT STRAINS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHARIATZADEH S.M.A.; HAMTA A.; SOLEYMANI MEHRANJANI M.; RASOULI ZAHRA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Arak University Medical Sciences Year:2009 | Volume:12 | Issue:2 (47) Page(s): 73-87

Download Full-Text

Persian Verion

View:

1,081

Download:

Cites:

Information Journal Paper

Title

DETERMINATION OF CHROMOSOMAL CHANGES IN DMBA-INDUCED SKIN CANCER IN SD RAT STRAINS

Author(s)

SHARIATZADEH S.M.A. | HAMTA A. | SOLEYMANI MEHRANJANI M. | RASOULI ZAHRA | Issue Writer Certificate

Keywords

DMBAQ3

SKIN CANCERQ3

SD RAT STRAINQ3

Abstract

Background: SKIN CANCER is one of the most important cancers in the world. This cancer is more common in men than women. We survey chromosomal changes in DMBA-induced SKIN CANCER in SD RAT STRAINs. Methods and Materials: In this fundamental study, 20 SD RAT STRAINs were randomly divided into case and contal group. DMBA (2.5 mg) was injected to SD RAT STRAINs subcutaneously; therefore SKIN CANCER model for studies was created. Tumors became subjects for cell culture and metaphase chromosomal was prepared. Finally G-banding was stained. We have also transmitted genomic information from rat to human using suitable databases and Gene was determined.Results: Data showed numerical and frequent structural changes in different number of chromosomes. For example; gain in chromosomes number 1, 15, 17 and loss in 1, 7, 15, and also structural changes like deletion was seen in chromosomes number 1, 4, 8, 10, 15, 17, and addition in chromosome number 15.Discussion: It is predicted that CST6, PRKCDBP, PTCH1, DKK3, BRMS1, CDKN1C, CD81, DMP1 CDKN2B, EEF1A1, HRAS, CASP2, KLF4 probably cause SKIN CANCER.

Cites

No record.

References

No record.

Cite

APA: Copy

SHARIATZADEH, S.M.A., HAMTA, A., SOLEYMANI MEHRANJANI, M., & RASOULI, ZAHRA. (2009). DETERMINATION OF CHROMOSOMAL CHANGES IN DMBA-INDUCED SKIN CANCER IN SD RAT STRAINS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 12(2 (47)), 73-87. SID. https://sid.ir/paper/69376/en

Vancouver: Copy

SHARIATZADEH S.M.A., HAMTA A., SOLEYMANI MEHRANJANI M., RASOULI ZAHRA. DETERMINATION OF CHROMOSOMAL CHANGES IN DMBA-INDUCED SKIN CANCER IN SD RAT STRAINS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2009;12(2 (47)):73-87. Available from: https://sid.ir/paper/69376/en

IEEE: Copy

S.M.A. SHARIATZADEH, A. HAMTA, M. SOLEYMANI MEHRANJANI, and ZAHRA RASOULI, “DETERMINATION OF CHROMOSOMAL CHANGES IN DMBA-INDUCED SKIN CANCER IN SD RAT STRAINS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 12, no. 2 (47), pp. 73–87, 2009, [Online]. Available: https://sid.ir/paper/69376/en

Related Journal Papers