Anti-parasitic Effects of Herbal Extract-Based Silver Nanoparticles on the Trophozoite and Cystic Forms of Acanthamoeba Protozoa

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KarimiPour Saryazdi Amir; GHAFFARIFAR FATEMEH; Tavakoli Pooya; KarimiPour Saryazdi Yeganeh; Zaki Leila; BAHADORY SAEED

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Journal Paper

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Journal: International Journal of Enteric Pathogens Year:2020 | Volume:8 | Issue:3 Page(s): 84-88

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Title

Anti-parasitic Effects of Herbal Extract-Based Silver Nanoparticles on the Trophozoite and Cystic Forms of Acanthamoeba Protozoa

Author(s)

Keywords

Acanthamoeba

Silver nanoparticles

Anti-parasitic

MTT

Flow cytometry

Abstract

Background: Acanthamoeba is a globally dispersed protozoan that can cause different clinical manifestations in infected individuals. Various drugs have been proposed against its drug-resistant forms. Objective: The present study examined Silver nanoparticles (NPs) with a good Anti-parasitic background. More precisely, the study focused on evaluating the Anti-parasitic effect of silver nano-scale particles on protozoan trophozoite and cysts by microscopic counting and Flow cytometry after exposure to different concentrations. Methods: To this end, MTT assay and IC50 were used to assess the macrophage toxicity and cysts/trophozoites, respectively. Results: Based on the results, 100 ppm silver NPs had better Anti-parasitic effects than 80 ppm concentration and even the standard treatment of Acanthamoeba on both trophozoite and cystic phases. Macrophages toxicity at 100 ppm concentration was similar to the control group. Conclusion: In general, further studies should be conducted to confirm the present results given the significant effects of silver NPs against trophozoite and parasite cysts.

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APA: Copy

KarimiPour Saryazdi, Amir, GHAFFARIFAR, FATEMEH, Tavakoli, Pooya, KarimiPour Saryazdi, Yeganeh, Zaki, Leila, & BAHADORY, SAEED. (2020). Anti-parasitic Effects of Herbal Extract-Based Silver Nanoparticles on the Trophozoite and Cystic Forms of Acanthamoeba Protozoa. INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN, 8(3), 84-88. SID. https://sid.ir/paper/695345/en

Vancouver: Copy

KarimiPour Saryazdi Amir, GHAFFARIFAR FATEMEH, Tavakoli Pooya, KarimiPour Saryazdi Yeganeh, Zaki Leila, BAHADORY SAEED. Anti-parasitic Effects of Herbal Extract-Based Silver Nanoparticles on the Trophozoite and Cystic Forms of Acanthamoeba Protozoa. INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN[Internet]. 2020;8(3):84-88. Available from: https://sid.ir/paper/695345/en

IEEE: Copy

Amir KarimiPour Saryazdi, FATEMEH GHAFFARIFAR, Pooya Tavakoli, Yeganeh KarimiPour Saryazdi, Leila Zaki, and SAEED BAHADORY, “Anti-parasitic Effects of Herbal Extract-Based Silver Nanoparticles on the Trophozoite and Cystic Forms of Acanthamoeba Protozoa,” INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN, vol. 8, no. 3, pp. 84–88, 2020, [Online]. Available: https://sid.ir/paper/695345/en

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