ANTIBIOTIC PROFILE OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS WITH MULTIPLE-DRUG RESISTANCES ISOLATED FROM NOSOCOMIAL INFECTIONS IN VALI-ASR HOSPITAL OF ARAK

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REZAZADEH M.; YOUSEFI MASHOUF R.; SARMADIAN H.; GHAZNAVIRAD E.

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Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2013 | Volume:16 | Issue:2 (71) Page(s): 30-37

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Title

ANTIBIOTIC PROFILE OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS WITH MULTIPLE-DRUG RESISTANCES ISOLATED FROM NOSOCOMIAL INFECTIONS IN VALI-ASR HOSPITAL OF ARAK

Author(s)

REZAZADEH M. | YOUSEFI MASHOUF R. | SARMADIAN H. | GHAZNAVIRAD E. | Issue Writer Certificate

Keywords

ANTIBIOTIC RESISTANCE PATTERNQ2

METHICILLIN-RESISTANCEQ2

STAPHYLOCOCCUS AUREUSQ2

Abstract

Background: STAPHYLOCOCCUS AUREUSis considered a common pathogenic factor in infections.Increase in infections caused by this bacterium in developing countries has led to many problems. The aim of this study is to identifythe antibiotic patterns of methicillin-resistant STAPHYLOCOCCUS AUREUS isolated from patients in the central hospital of Arak.Materials and Methods: In this descriptive cross-sectional study, a total of 100 samples were isolated from hospital patients during one year. The isolates sensitivity to cefoxitin and oxacilin disks were evaluated through disk diffusion. Using polymerase chain reaction (PCR), the isolates were tested for the presence of mecA gene. Finally, antibacterial resistance patterns of the isolates to 13 antibiotics were determined.Results: In this study, 80 samples in a total of 100 isolates of STAPHYLOCOCCUS AUREUS were methicillin-resistant. Evaluation and assessment of antibiotic resistance showed the greatest resistance to penicillin (100%), tetracycline (88.50%), levofloxacin (85.70%), and ciprofloxacin (85.70%), respectively, while the lowest levels of resistance were observed to antibiotics chloramphenicol (5.70%), netilmicin (5.70%), and mupirocin (0%), respectively.Conclusion: This study showed increased resistance to different antibiotics in STAPHYLOCOCCUS AUREUSthat is a serious warning to the treatment of infections caused by this bacterium in the region.Therefore, in order to prevent increased resistance to other antibiotics, it is essential to withhold prescriptions and unessential use of available antibiotics.

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APA: Copy

REZAZADEH, M., YOUSEFI MASHOUF, R., SARMADIAN, H., & GHAZNAVIRAD, E.. (2013). ANTIBIOTIC PROFILE OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS WITH MULTIPLE-DRUG RESISTANCES ISOLATED FROM NOSOCOMIAL INFECTIONS IN VALI-ASR HOSPITAL OF ARAK. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 16(2 (71)), 30-37. SID. https://sid.ir/paper/69536/en

Vancouver: Copy

REZAZADEH M., YOUSEFI MASHOUF R., SARMADIAN H., GHAZNAVIRAD E.. ANTIBIOTIC PROFILE OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS WITH MULTIPLE-DRUG RESISTANCES ISOLATED FROM NOSOCOMIAL INFECTIONS IN VALI-ASR HOSPITAL OF ARAK. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2013;16(2 (71)):30-37. Available from: https://sid.ir/paper/69536/en

IEEE: Copy

M. REZAZADEH, R. YOUSEFI MASHOUF, H. SARMADIAN, and E. GHAZNAVIRAD, “ANTIBIOTIC PROFILE OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS WITH MULTIPLE-DRUG RESISTANCES ISOLATED FROM NOSOCOMIAL INFECTIONS IN VALI-ASR HOSPITAL OF ARAK,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 16, no. 2 (71), pp. 30–37, 2013, [Online]. Available: https://sid.ir/paper/69536/en

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