THE EFFECT OF GABAPENTIN ON CONTROLLING NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY

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NOROUZI A.; FATEH SH.; RAHBARI E.

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Paper Information

Journal: Journal of Arak University Medical Sciences Year:2012 | Volume:15 | Issue:4 (63) Page(s): 70-75

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Title

THE EFFECT OF GABAPENTIN ON CONTROLLING NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY

Author(s)

NOROUZI A. | FATEH SH. | RAHBARI E. | Issue Writer Certificate

Keywords

GABAPENTINQ2

LAPAROSCOPIC CHOLECYSTECTOMYQ2

NAUSEAQ3

VOMITINGQ3

Abstract

Background: NAUSEA and VOMITING are prevalent after LAPAROSCOPIC CHOLECYSTECTOMY surgery and physicians need to use drugs, such as ondansetron, propofol, metoclopramide, and ramostrogen, for controlling them. This study was done to evaluate the effect of GABAPENTIN 300mg and 600mg administration on controlling NAUSEA and VOMITING after LAPAROSCOPIC CHOLECYSTECTOMY surgery.Materials and Methods: In this clinical trial, 105 ASA patients (classes 1 and 2) were randomly divided into 3 equal groups including placebo group, 300 mg GABAPENTIN group, and 600 mg GABAPENTIN group. The same technique of anesthesia was used for all groups. The patients were controlled for NAUSEA and VOMITING each 2 to 6 hours and after that every 4 to 18 hours. Data were analyzed using SPSS software.Results: The mean degree of NAUSEA in the control group was 2.8, in second group which took 300 mg GABAPENTIN was 0.67, and in third group which took 600 mg of GABAPENTIN was 0.55 (p<0.001).In addition, the severity of VOMITING in the control group was 0.326, in second group was 0.126, and in third group was 0.053 (p<0.001).Conclusion: Administration of one dose of 300 mg GABAPENTIN can reduce NAUSEA and VOMITING, and with increasing GABAPENTIN dosage to 600 mg, these complications will decrease even more. Therefore, using GABAPENTIN in LAPAROSCOPIC CHOLECYSTECTOMY surgery is recommended.

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APA: Copy

NOROUZI, A., FATEH, SH., & RAHBARI, E.. (2012). THE EFFECT OF GABAPENTIN ON CONTROLLING NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 15(4 (63)), 70-75. SID. https://sid.ir/paper/69681/en

Vancouver: Copy

NOROUZI A., FATEH SH., RAHBARI E.. THE EFFECT OF GABAPENTIN ON CONTROLLING NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2012;15(4 (63)):70-75. Available from: https://sid.ir/paper/69681/en

IEEE: Copy

A. NOROUZI, SH. FATEH, and E. RAHBARI, “THE EFFECT OF GABAPENTIN ON CONTROLLING NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 15, no. 4 (63), pp. 70–75, 2012, [Online]. Available: https://sid.ir/paper/69681/en

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