THE EFFECT OF AEROBIC TRAINING ON METABOLIC PARAMETERS AND SERUM LEVEL OF SIRTUIN1 IN WOMEN WITH TYPE 2 DIABETES

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SAREMI ABBAS; SHAHRJERDI SHAHNAZ; KAVYANI ATEFE

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Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2016 | Volume:19 | Issue:9 (114) Page(s): 88-97

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Title

THE EFFECT OF AEROBIC TRAINING ON METABOLIC PARAMETERS AND SERUM LEVEL OF SIRTUIN1 IN WOMEN WITH TYPE 2 DIABETES

Author(s)

SAREMI ABBAS | SHAHRJERDI SHAHNAZ | KAVYANI ATEFE | Issue Writer Certificate

Keywords

AEROBIC EXERCISEQ1

CALORIC RESTRICTIONQ1

SIRTUIN-1Q1

TYPE 2 DIABETESQ1

Abstract

Background: SIRTUIN-1 regulates important cellular processes, including apoptosis, cellular senescence, and metabolism. Therefore, SIRTUIN-1 may be a novel therapeutic target for TYPE 2 DIABETES. The aim of this study was to investigate the effect of 8 weeks aerobic training on SIRTUIN-1 level and cardiometabolic parameters in women with TYPE 2 DIABETES.Materials and Methods: In this semi-experimental study with pretest – posttest design, twenty diabetic women (aged 43.92±5.2 y) were randomly assigned to aerobic training or non-exercising control groups. Aerobic training program was performed 50-60 min/d, 3d/wk, for 2 months. Serum levels of SIRTUIN-1, body composition and metabolic parameters were assessed before and after the training period.Data were analyzed by paired T test.Results: Adiposity indices, total cholesterol, triglyceride, LDL- cholesterol,blood glucose and insulin resistance index were significantly reduced in the intervention group compared to the control (p<0.05). Also, SIRTUIN-1 level was increased in the intervention group compared to the control (p<0.05).Conclusion: These findings show that AEROBIC EXERCISE is associated with an improvement in siruin-1 levels and metabolic indices in women with TYPE 2 DIABETES.

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APA: Copy

SAREMI, ABBAS, SHAHRJERDI, SHAHNAZ, & KAVYANI, ATEFE. (2016). THE EFFECT OF AEROBIC TRAINING ON METABOLIC PARAMETERS AND SERUM LEVEL OF SIRTUIN1 IN WOMEN WITH TYPE 2 DIABETES. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 19(9 (114)), 88-97. SID. https://sid.ir/paper/69838/en

Vancouver: Copy

SAREMI ABBAS, SHAHRJERDI SHAHNAZ, KAVYANI ATEFE. THE EFFECT OF AEROBIC TRAINING ON METABOLIC PARAMETERS AND SERUM LEVEL OF SIRTUIN1 IN WOMEN WITH TYPE 2 DIABETES. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2016;19(9 (114)):88-97. Available from: https://sid.ir/paper/69838/en

IEEE: Copy

ABBAS SAREMI, SHAHNAZ SHAHRJERDI, and ATEFE KAVYANI, “THE EFFECT OF AEROBIC TRAINING ON METABOLIC PARAMETERS AND SERUM LEVEL OF SIRTUIN1 IN WOMEN WITH TYPE 2 DIABETES,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 19, no. 9 (114), pp. 88–97, 2016, [Online]. Available: https://sid.ir/paper/69838/en

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