THE EFFECT OF EIGHT WEEKS OF AEROBIC EXERCISE ON PLASMA LEVELS OF PARAOXONASE-1 AND LIPID HYDROPEROXIDE IN DIABETIC MALE RATS TREATED WITH CHLORELLA ALGAE

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KHANZADEH N.; POOZESH JADIDI R.; NOUR AZAR M.A.

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Journal: Journal of Rafsanjan University of Medical Sciences Year:2018 | Volume:17 | Issue:2 Page(s): 131-142

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Title

THE EFFECT OF EIGHT WEEKS OF AEROBIC EXERCISE ON PLASMA LEVELS OF PARAOXONASE-1 AND LIPID HYDROPEROXIDE IN DIABETIC MALE RATS TREATED WITH CHLORELLA ALGAE

Author(s)

KHANZADEH N. | POOZESH JADIDI R. | NOUR AZAR M.A. | Issue Writer Certificate

Keywords

DIABETESQ2

AEROBIC EXERCISEQ2

ALGAE CHLORELLAQ1

PARAOXONASE-1Q2

LIPID HYDROPEROXIDEQ1

RATQ2

Abstract

Background and Objectives: AEROBIC EXERCISE and taking chlorella supplementation to control oxidative stress markers and PARAOXONASE-1 (PON1) levels in diabetic patients is of great importance. So, the aim of the present research was to investigate the effect of eight-week AEROBIC EXERCISE on PARAOXONASE-1 and LIPID HYDROPEROXIDE plasma levels in diabetic Wistar RATs treated with chlorella algae.Material and Methods: The present study was an experimental research. 50 male Wistar RATs were randomly divided into 5 groups of 10: control, diabetic, diabetic with taking supplement (colorella), diabetic with training, and combined diabetic (training+supplement) groups. Training and taking supplement continued for 8 weeks after DIABETES induction; at the end of the 8th week, the levels of PARAOXONASE-1 and LIPID HYDROPEROXIDE were measured. Data were analyzed using one-way ANOVA and Tukey’s post hoc test.Results: The results showed that there were significant differences between the groups in terms of PARAOXONASE-1 (p=0.001). Comparison between the groups of chlorella and training (p=0.001) and the combined and chlorella (p=0.001) as well as the exercise and combined (p=0.007) showed a significant difference. Also, there were significant differences between the groups in terms of LIPID HYDROPEROXIDE (p=0.001). So that there was a significant difference between the training and chlorella (p=0.005) and combined groups (p=0.001) and the combined and exercise groups (p=0.029). So that in the combined group, paraoxonase -1 was further increased.Conclusion: Eight weeks of aerobic training along with taking chlorella can remarkably reduce LIPID HYDROPEROXIDE and increase PARAOXONASE-1 in RATs with DIABETES; However, their separate protocls can be also useful.

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APA: Copy

KHANZADEH, N., POOZESH JADIDI, R., & NOUR AZAR, M.A.. (2018). THE EFFECT OF EIGHT WEEKS OF AEROBIC EXERCISE ON PLASMA LEVELS OF PARAOXONASE-1 AND LIPID HYDROPEROXIDE IN DIABETIC MALE RATS TREATED WITH CHLORELLA ALGAE. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 17(2 ), 131-142. SID. https://sid.ir/paper/71281/en

Vancouver: Copy

KHANZADEH N., POOZESH JADIDI R., NOUR AZAR M.A.. THE EFFECT OF EIGHT WEEKS OF AEROBIC EXERCISE ON PLASMA LEVELS OF PARAOXONASE-1 AND LIPID HYDROPEROXIDE IN DIABETIC MALE RATS TREATED WITH CHLORELLA ALGAE. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2018;17(2 ):131-142. Available from: https://sid.ir/paper/71281/en

IEEE: Copy

N. KHANZADEH, R. POOZESH JADIDI, and M.A. NOUR AZAR, “THE EFFECT OF EIGHT WEEKS OF AEROBIC EXERCISE ON PLASMA LEVELS OF PARAOXONASE-1 AND LIPID HYDROPEROXIDE IN DIABETIC MALE RATS TREATED WITH CHLORELLA ALGAE,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 17, no. 2 , pp. 131–142, 2018, [Online]. Available: https://sid.ir/paper/71281/en

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