QUANTITATIVE ASSESSMENT OF CONCENTRATION OF PHARMACEUTICAL POLLUTANTS (NAPROXEN, DICLOFENAC, AND CELECOXIB) IN THE KARAJ RIVER, ALBORZ PROVINCE, IRAN

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MORTAZAVI S.; NOROUZI FARD P.; ANBARNEJHAD S.

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Journal Paper

Paper Information

Journal: Journal of Rafsanjan University of Medical Sciences Year:2017 | Volume:16 | Issue:7 Page(s): 605-622

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Title

QUANTITATIVE ASSESSMENT OF CONCENTRATION OF PHARMACEUTICAL POLLUTANTS (NAPROXEN, DICLOFENAC, AND CELECOXIB) IN THE KARAJ RIVER, ALBORZ PROVINCE, IRAN

Author(s)

MORTAZAVI S. | NOROUZI FARD P. | ANBARNEJHAD S. | Issue Writer Certificate

Keywords

PHARMACEUTICAL POLLUTANTQ1

WATER TREATMENTQ2

RIVERQ2

ANALGESICQ3

HPLCQ3

KARAJQ2

Abstract

Background and Objectives: Aquatic ecosystems, especially RIVERs that pass through densely populated residential areas are utilized more than any other resource for a variety of uses and can have great effects on environment and human health. KARAJ RIVER in Alborz province is one of the largest aquatic ecosystems along which three important treatment plants are established.Materials and Methods: Since long-term toxicity and retention are main features of pharmaceutical contaminants in the aquatic environment, present research aimed to evaluate anti-inflammatory drugs, concentrations of naproxen, diclofenac, and celecoxib in KARAJ RIVER with samples from 14 sites along the RIVER, 6 stations, and the wastewater treatment plants. After preparation and filtration of samples, the concentrations of drugs were measured by HPLC.Results: The results showed that the average concentrations of drugs in the KARAJ RIVER water were as follow: 0.409 mg/l naproxen, 0.091 mg/l celecoxib, and 0.034 mg/l diclofenac. In the wastewater treatment plant and its sewer, the drugs concentrations were 0.774 and 0.566 mg/l naproxen, 0.260 and 0.171 mg/l celecoxib, and 0.082 and 0.064 mg/l diclofenac, respectively.Conclusion: Their reducing trend can be found in sewer, wastewater, and water with the highest concentration of naproxen and lowest concentration of diclofenac. The correlation between the pollutants in different samples may indicate inefficiency of the treatment plants and retention of the pollutants that are discharged into the RIVER through the wastewater. For this, in order to protect environment it is essential to use effective methods of treatment.

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APA: Copy

MORTAZAVI, S., NOROUZI FARD, P., & ANBARNEJHAD, S.. (2017). QUANTITATIVE ASSESSMENT OF CONCENTRATION OF PHARMACEUTICAL POLLUTANTS (NAPROXEN, DICLOFENAC, AND CELECOXIB) IN THE KARAJ RIVER, ALBORZ PROVINCE, IRAN. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 16(7 ), 605-622. SID. https://sid.ir/paper/71412/en

Vancouver: Copy

MORTAZAVI S., NOROUZI FARD P., ANBARNEJHAD S.. QUANTITATIVE ASSESSMENT OF CONCENTRATION OF PHARMACEUTICAL POLLUTANTS (NAPROXEN, DICLOFENAC, AND CELECOXIB) IN THE KARAJ RIVER, ALBORZ PROVINCE, IRAN. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2017;16(7 ):605-622. Available from: https://sid.ir/paper/71412/en

IEEE: Copy

S. MORTAZAVI, P. NOROUZI FARD, and S. ANBARNEJHAD, “QUANTITATIVE ASSESSMENT OF CONCENTRATION OF PHARMACEUTICAL POLLUTANTS (NAPROXEN, DICLOFENAC, AND CELECOXIB) IN THE KARAJ RIVER, ALBORZ PROVINCE, IRAN,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 16, no. 7 , pp. 605–622, 2017, [Online]. Available: https://sid.ir/paper/71412/en

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