THE EFFECT OF DIFFERENT LIPIDS ON PHYSICOCHEMICAL CHARACTERISTICS AND STAIBILITY OF PHYCOCYANIN-LOADED SOLID LIPID NANOPARTICLES

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SEYED YAGOUBI A.; SHAHIDI F.; MOHEBBI M.; VARIDI M.; GOLMOHAMMADZADEH SH.

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Journal: IRANIAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY Year:2017 | Volume:14 | Issue:67 Page(s): 83-93

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Title

THE EFFECT OF DIFFERENT LIPIDS ON PHYSICOCHEMICAL CHARACTERISTICS AND STAIBILITY OF PHYCOCYANIN-LOADED SOLID LIPID NANOPARTICLES

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NANOCARRIERSQ1

STABILITYQ2

PHYCOCYANINQ1

Abstract

The aim of this study, was to evaluate the effect of different percentages of lipid contain 100% glycerol distearate (GDS), glycerol monostearate (GMS), stearic acid (SA) and lipid composition of 50: 50 GDS: GMS, 50: 50 GDS: SA and 50: 50 SA: GMS on the physicochemical properties of PHYCOCYANIN-loaded solid lipid nanoparticles. The results showed that the use of GDS due to the different structure and having an irregular lipid network had the better encapsulation efficiency in compared with other lipids. The minimum particle size, maximum zeta potential and minimum polydispersity index were belongs to formulations no.2, 6 and 1 respectively. The results indicated that GDS in compared with other lipids had better STABILITY during 6 months and the lowest desposition and adhesion of the particles were observed in this type of lipid. The produced NANOCARRIERS had encapsulation efficieny ranging of 39.80 to 62.38. TEM, DSC and as well as FTIR were also employed to evaluate the morphological characteristics, thermal behavior and chemical structure of lipid nanoparticles.

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APA: Copy

SEYED YAGOUBI, A., SHAHIDI, F., MOHEBBI, M., VARIDI, M., & GOLMOHAMMADZADEH, SH.. (2017). THE EFFECT OF DIFFERENT LIPIDS ON PHYSICOCHEMICAL CHARACTERISTICS AND STAIBILITY OF PHYCOCYANIN-LOADED SOLID LIPID NANOPARTICLES. IRANIAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 14(67), 83-93. SID. https://sid.ir/paper/71628/en

Vancouver: Copy

SEYED YAGOUBI A., SHAHIDI F., MOHEBBI M., VARIDI M., GOLMOHAMMADZADEH SH.. THE EFFECT OF DIFFERENT LIPIDS ON PHYSICOCHEMICAL CHARACTERISTICS AND STAIBILITY OF PHYCOCYANIN-LOADED SOLID LIPID NANOPARTICLES. IRANIAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY[Internet]. 2017;14(67):83-93. Available from: https://sid.ir/paper/71628/en

IEEE: Copy

A. SEYED YAGOUBI, F. SHAHIDI, M. MOHEBBI, M. VARIDI, and SH. GOLMOHAMMADZADEH, “THE EFFECT OF DIFFERENT LIPIDS ON PHYSICOCHEMICAL CHARACTERISTICS AND STAIBILITY OF PHYCOCYANIN-LOADED SOLID LIPID NANOPARTICLES,” IRANIAN JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, vol. 14, no. 67, pp. 83–93, 2017, [Online]. Available: https://sid.ir/paper/71628/en

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