مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Comparative volatile composition, antioxidant and cytotoxic evaluation of the essential oil of Zhumeria majdae from south of Iran

Pages

  80-85

Abstract

 Objective(s): The purpose of this study was to evaluate variations in yields, volatile composition and biological activities of Essential oils (EOs) obtained from the aerial parts of Zhumeria majdae collected from five localities of the south of Iran. Materials and Methods: The EOs were analyzed using gas chromatography and gas chromatography-mass spectrometry techniques. The Antioxidant activity of the EOs was tested using DPPH and β-carotene/linoleic acid assays. In vitro Cytotoxicity was tested against two cancer cell lines (A375 and MCF7) using MTT assay. Results: The oils yield varied from 6. 3% (S2) to 10. 2% (V/W) (S4). All of five investigated EOs samples presented three major compounds: linalool (24. 4-34. 6%), camphor (26. 1-34. 7%) and translinalool oxide (7. 6-28. 6%). Although the main constituents were common, their percentages were different. Among samples, S1 had a better Antioxidant activity in both DPPH and β-carotene/linoleic acid methods (IC50= 8. 01 and 11. 77 mg/ml, respectively). In vitro Cytotoxicity against two cancer cell lines of human melanoma cell line (A375) and breast cancer cell line (MCF7), showed a moderate Cytotoxicity of S3 against A375 cells with IC50 value of 624 μ g/ml. Conclusion: Tangezagh (S4) plant materials revealed the highest level of oil yield as the region is recommended for collecting the plant samples. Taken together, despite the weak antioxidant and moderate cytotoxic activities of tested EOs, this study suggested a proper potential for possible use of the EOs of Z. majdae for pharmaceutical and perfume industries.

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    Cite

    APA: Copy

    Saeidi, Mansoor, ASILI, JAVAD, EMAMI, SEYED AHMAD, MOSHTAGHI, NASRIN, & MALEKZADEH SHAFAROUDI, SAEID. (2019). Comparative volatile composition, antioxidant and cytotoxic evaluation of the essential oil of Zhumeria majdae from south of Iran. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 22(1), 80-85. SID. https://sid.ir/paper/722239/en

    Vancouver: Copy

    Saeidi Mansoor, ASILI JAVAD, EMAMI SEYED AHMAD, MOSHTAGHI NASRIN, MALEKZADEH SHAFAROUDI SAEID. Comparative volatile composition, antioxidant and cytotoxic evaluation of the essential oil of Zhumeria majdae from south of Iran. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2019;22(1):80-85. Available from: https://sid.ir/paper/722239/en

    IEEE: Copy

    Mansoor Saeidi, JAVAD ASILI, SEYED AHMAD EMAMI, NASRIN MOSHTAGHI, and SAEID MALEKZADEH SHAFAROUDI, “Comparative volatile composition, antioxidant and cytotoxic evaluation of the essential oil of Zhumeria majdae from south of Iran,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 22, no. 1, pp. 80–85, 2019, [Online]. Available: https://sid.ir/paper/722239/en

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