EFFECT OF BETADINE ON WOUND HEALINGIN RAT

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TAVAKOLI R.; NABIPOUR F.; NAJAFIPOUR H.

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Journal: JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS) Year:2006 | Volume:8 | Issue:3 (31) Page(s): 7-12

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Title

EFFECT OF BETADINE ON WOUND HEALINGIN RAT

Author(s)

TAVAKOLI R. | NABIPOUR F. | NAJAFIPOUR H. | Issue Writer Certificate

Keywords

BETADINEQ3

WOUND HEALINGQ2

RATQ3

Abstract

BACKGROUND & OBJECTIVE: BETADINE is a disinfectant routinely used in all of the Iranian health centers and many other countries in the world but its effect on WOUND HEALING is controversial. The aim of this study was to investigate the effect of beta dine on WOUND HEALING in RAT.METHODS: In this interventional study, two groups of RATs (n=10 each) were randomized as BETADINE and control groups. Under nesdonal anesthesia, a full thickness skin in an area of 2 cm2 was excised on dorsal neck of RATs and immediately BETADINE was applied in BETADINE group. Control group received no treatment. Wound area, percentage of recovery and body weight was measured on postoperative days 1, 4, 7 and 10. Number of fibroblasts, collagen fibers, new vessels, lymphocytes, macrophages, neutrophils and thickness of epiderm were determined in three groups by biopsy on day 10. FINDINGS: The results showed the percentage of recovery was not significantly different in the 4th, 7th and 10th days.Revascularisation, fibroblasts, lymphocytes, neutrophils, epidennal depth and collagen fibers were not significantly different between two groups. Macrophages in the BETADINE group were significantly higher than control group (p<0.01).CONCLUSON: The results propose that BETADINE not only does not speed up WOUND HEALING but also delays the inflammatory phase.

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APA: Copy

TAVAKOLI, R., NABIPOUR, F., & NAJAFIPOUR, H.. (2006). EFFECT OF BETADINE ON WOUND HEALINGIN RAT. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 8(3 (31)), 7-12. SID. https://sid.ir/paper/73083/en

Vancouver: Copy

TAVAKOLI R., NABIPOUR F., NAJAFIPOUR H.. EFFECT OF BETADINE ON WOUND HEALINGIN RAT. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2006;8(3 (31)):7-12. Available from: https://sid.ir/paper/73083/en

IEEE: Copy

R. TAVAKOLI, F. NABIPOUR, and H. NAJAFIPOUR, “EFFECT OF BETADINE ON WOUND HEALINGIN RAT,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 8, no. 3 (31), pp. 7–12, 2006, [Online]. Available: https://sid.ir/paper/73083/en

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