SKIN AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH THALASSEMIA MAJOR

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MOMENI A.; ADABI M.; AMIN JAVAHERI M.A.S.; HOUR FAR H.

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Paper Information

Journal: Journal of Babol University of Medical Sciences Year:2001 | Volume:3 | Issue:2 (10) Page(s): 38-46

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Information Journal Paper

Title

SKIN AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH THALASSEMIA MAJOR

Author(s)

MOMENI A. | ADABI M. | AMIN JAVAHERI M.A.S. | HOUR FAR H. | Issue Writer Certificate

Keywords

THALASSEMIAQ3

SKIN MANTIFESTATIONSQ4

MUCOSAL MANIFESTATIONSQ3

Abstract

OBJECTIVE: β - THALASSEMIA major is one of the common genetic disorders in Iran. In Isfahan, the prevalence of gene carriers is about 8%. As yet, no many information about skin manifestations of these patients has been published. This study was done to evaluate skin manifestations in THALASSEMIA major patients and compared them with laboratory and pathologic findings. METHODS: 367 cases of β -THALASSEMIAmajor who referred to this center, were clinically examined during (1998-99). Routine and special lab tests were done on all cases and skin biopsy was done on selected cases. The findings were analyzed by statistical methods and compared with the sex, age, serum ferritin, thyroid hormone level, liver enzymes and amount of injected desferal. FINDINGS: Skin dryness (53%), freckling (33%), lentigo (28%), coarse hair (24%), scar and hyperpigmentation at the desferal injection site (28% & 30% respectively), distal nail brittlleness (23%), nail plate roughness (21%) and hard palate pigmentation (30%) were the most common findings. Some skin lesions related to age, sex, serum ferritin level, thyroid hormone and hemoglobin. A11lesions, except hair and skin dryness, were severe in older patients. CONCLUSION: Skin and MUCOSAL MANIFESTATIONS are common in THALASSEMIA major cases. Most manifestations are related to iron deposition in skin and other organs and incomplete treatment by present methods.

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APA: Copy

MOMENI, A., ADABI, M., AMIN JAVAHERI, M.A.S., & HOUR FAR, H.. (2001). SKIN AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH THALASSEMIA MAJOR. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 3(2 (10)), 38-46. SID. https://sid.ir/paper/73747/en

Vancouver: Copy

MOMENI A., ADABI M., AMIN JAVAHERI M.A.S., HOUR FAR H.. SKIN AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH THALASSEMIA MAJOR. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2001;3(2 (10)):38-46. Available from: https://sid.ir/paper/73747/en

IEEE: Copy

A. MOMENI, M. ADABI, M.A.S. AMIN JAVAHERI, and H. HOUR FAR, “SKIN AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH THALASSEMIA MAJOR,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 3, no. 2 (10), pp. 38–46, 2001, [Online]. Available: https://sid.ir/paper/73747/en

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