Comparison of 8-Hydroxy Deoxyguanosine Level in the Saliva between the Patients with Recurrent Aphthous Stomatitis and Healthy Individuals

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Omidpanah Neda; MOMEN BEITOLLAHI JALIL; Goodarzi Mohamad

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Journal: Journal of Mashhad Dental School Year:2019 | Volume:42 | Issue:4 Page(s): 278-284

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Title

Comparison of 8-Hydroxy Deoxyguanosine Level in the Saliva between the Patients with Recurrent Aphthous Stomatitis and Healthy Individuals

Author(s)

Omidpanah Neda | MOMEN BEITOLLAHI JALIL | Goodarzi Mohamad | Issue Writer Certificate

Keywords

8-OHdGQ1

Recurrent Aphthous StomatitisQ1

SalivaQ2

Oxidative StressQ1

Abstract

Introduction: Hydroxydeoxyguanosine (8-OHdG) is a product of DNA damage. Considering the role of Oxidative Stress in the etiopathogenesis of Recurrent Aphthous Stomatitis, the present study aimed to evaluate the DNA damage caused by Oxidative Stress in these patients. Materials and Methods: This case-control study was conducted on 30 patients with Recurrent Aphthous Stomatitis and 30 healthy subjects. The subjects were matched in terms of age and gender. The inclusion criteria for enrollment were the absence of systemic diseases, no drug use, no tobacco and alcohol use, and no use of antioxidant supplements for the past 3 months. The inclusion criterion for recruitment in the study groups was the presence of a recurrent aphthous ulcer for a minimum of three times per year. Unstimulated Saliva sampling was performed. Data were analyzed by t-student. Conclusion: No significant difference was observed between the patients with Recurrent Aphthous Stomatitis and healthy subjects regarding the level of 8-OHdG (P=0. 427).

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APA: Copy

Omidpanah, Neda, MOMEN BEITOLLAHI, JALIL, & Goodarzi, Mohamad. (2019). Comparison of 8-Hydroxy Deoxyguanosine Level in the Saliva between the Patients with Recurrent Aphthous Stomatitis and Healthy Individuals. JOURNAL OF MASHHAD DENTAL SCHOOL, 42(4 ), 278-284. SID. https://sid.ir/paper/74222/en

Vancouver: Copy

Omidpanah Neda, MOMEN BEITOLLAHI JALIL, Goodarzi Mohamad. Comparison of 8-Hydroxy Deoxyguanosine Level in the Saliva between the Patients with Recurrent Aphthous Stomatitis and Healthy Individuals. JOURNAL OF MASHHAD DENTAL SCHOOL[Internet]. 2019;42(4 ):278-284. Available from: https://sid.ir/paper/74222/en

IEEE: Copy

Neda Omidpanah, JALIL MOMEN BEITOLLAHI, and Mohamad Goodarzi, “Comparison of 8-Hydroxy Deoxyguanosine Level in the Saliva between the Patients with Recurrent Aphthous Stomatitis and Healthy Individuals,” JOURNAL OF MASHHAD DENTAL SCHOOL, vol. 42, no. 4 , pp. 278–284, 2019, [Online]. Available: https://sid.ir/paper/74222/en

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