COMPARISON OF THE EFFECTS OF TOPICAL HYDROCORTISON AND CLOBETASOLE PHONOPHORESIS ON REDUCTION OF PAIN IN OSTEOARTHRITIC KNEE JOINT

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SEDGHIMEHR T.; BAHRPEYMA F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Physiology and Pharmacology Year:2006 | Volume:10 | Issue:3 Page(s): 247-258

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Title

COMPARISON OF THE EFFECTS OF TOPICAL HYDROCORTISON AND CLOBETASOLE PHONOPHORESIS ON REDUCTION OF PAIN IN OSTEOARTHRITIC KNEE JOINT

Author(s)

SEDGHIMEHR T. | BAHRPEYMA F. | Issue Writer Certificate

Keywords

PHONOPHORESISQ3

HYDROCORTISONEQ3

CLOBETASOLEQ3

OSTEOARTHRITQ3

Abstract

Introduction: PHONOPHORESIS is the use of ultrasound to enhancing cellular drug delivery through the skin. In this study the effect of clobethasole and HYDROCORTISONE ointments PHONOPHORESIS on pain, knee OSTEOARTHRITis and some other symptoms was studied.Methods: An experimental single blind randomized clinical trial (RCT) was used. An available sampling technique was used for selection of patients. Sixty subjects with OSTEOARTHRITis knee (tibiofemoral) joints were randomly assigned to six groups: 1-Ultrasound with acoustic gel. 2- Placebo ultrasound with HYDROCORTISONE. 3- Placebo ultrasound with CLOBETASOLE. 4- HYDROCORTISONE PHONOPHORESIS. 5- CLOBETASOLE PHONOPHORESIS. 6- Placebo ultrasound with acoustic gel. All of the patients received treatments for ten sessions. Pain level was determined by visual analog scale (VAS) at the beginning, day 6 and follow up day (11th session). Edema and knee range of motion (ROM) were measured at the beginning, day 4, day 7 and follow up day. 20 meters walking test time was measured at the beginning and follow up day. Wilcoxon and Friedman statistical tests were used to analyze data.Results: At the end of treatment sessions; groups 1, 4, 5 showed a significant decrease in pain and edema and an increase in knee ROM and 20 meters walking test time (P < 0.05). Additionally, there was a significant difference in improvement rates between group 5 and groups 1 and 4.Conclusion: This study showed that both HYDROCORTISONE and CLOBETASOLE PHONOPHORESIS were more effective than ultrasound and acoustic gel on OSTEOARTHRITis pain of knee joint. CLOBETASOLE has a faster effect than other treatments.

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APA: Copy

SEDGHIMEHR, T., & BAHRPEYMA, F.. (2006). COMPARISON OF THE EFFECTS OF TOPICAL HYDROCORTISON AND CLOBETASOLE PHONOPHORESIS ON REDUCTION OF PAIN IN OSTEOARTHRITIC KNEE JOINT. PHYSIOLOGY AND PHARMACOLOGY, 10(3), 247-258. SID. https://sid.ir/paper/75071/en

Vancouver: Copy

SEDGHIMEHR T., BAHRPEYMA F.. COMPARISON OF THE EFFECTS OF TOPICAL HYDROCORTISON AND CLOBETASOLE PHONOPHORESIS ON REDUCTION OF PAIN IN OSTEOARTHRITIC KNEE JOINT. PHYSIOLOGY AND PHARMACOLOGY[Internet]. 2006;10(3):247-258. Available from: https://sid.ir/paper/75071/en

IEEE: Copy

T. SEDGHIMEHR, and F. BAHRPEYMA, “COMPARISON OF THE EFFECTS OF TOPICAL HYDROCORTISON AND CLOBETASOLE PHONOPHORESIS ON REDUCTION OF PAIN IN OSTEOARTHRITIC KNEE JOINT,” PHYSIOLOGY AND PHARMACOLOGY, vol. 10, no. 3, pp. 247–258, 2006, [Online]. Available: https://sid.ir/paper/75071/en

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