ASSESMENT OF FLAXSEED ON OXIDATIVE STRESS IN PREPUBERTAL RATS WITH EXPERIMENTAL VARICOCELE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SOHRABIPOUR SHAHLA; JAFARI ADELEH; KAMALINEJAD MOHAMAD; SARRAFNEJD ABDOLFATAH; SHAHRESTANY TAHERAH; SADEGHIPOUR HAMID REZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Physiology and Pharmacology Year:2011 | Volume:15 | Issue:3 Page(s): 415-426

Download Full-Text

Persian Verion

View:

714

Download:

Cites:

Information Journal Paper

Title

ASSESMENT OF FLAXSEED ON OXIDATIVE STRESS IN PREPUBERTAL RATS WITH EXPERIMENTAL VARICOCELE

Author(s)

Keywords

SUPEROXIDE ANIONQ3

STRESS OXIDATIVEQ2

VARICOCELEQ2

FLAXSEEDQ2

TOTAL ANTIOXIDANT CAPACITYQ2

Abstract

Introduction: Perepubertal VARICOCELE can result in hypotrophy of testes, sperm damage and decrease the function of leydig cells in future. pathophysiology of VARICOCELE is unclear. Increased reactive oxygen species (ROS) is a major theory. There are many controversies in treatment of pediatric VARICOCELE. FLAXSEED (FS) is the richest source of lignans with antioxidant properties. The aim of this study was to investigate effect of FLAXSEED on oxidative stress in prepubertal rats with experimental VARICOCELE.Methods: 35 male prepubertal rats were divided into 5 groups: control, sham, sham that fed base diet which was supplemented with 10% FS, VARICOCELE, VARICOCELE that fed base diet which was supplemented with 10% FS. Animals were sacrificed six weeks later. Sperm SUPEROXIDE ANION and H2O2 production, MDA in testis and TOTAL ANTIOXIDANT CAPACITY in semen were evaluated.Results: Intracellular SUPEROXIDE ANION and H2O2 production was significantly higher in VARICOCELE induced group (P£0.001), but FS significantly decreased them (P£0.001). There was no significant difference for seminal plasma total antioxidant activity among all groups (P³0.05). Left testicular MDA concentration of rats with VARICOCELE that were fed by FS 10% was lower compared with VARICOCELE groups (P£0.05).Conclusion: Fs as a fat soluble antioxidant can protect the sperm membrane from the damage induced by ROS through its effective antioxidant potential.

Cites

Effect of Flaxseed Supplementation and Concurrent Physical Activity on Total Antioxidant Capacity of the Plasma and the Lipid Peroxidation Index of Overweight Womcven

References

No record.

Cite

APA: Copy

SOHRABIPOUR, SHAHLA, JAFARI, ADELEH, KAMALINEJAD, MOHAMAD, SARRAFNEJD, ABDOLFATAH, SHAHRESTANY, TAHERAH, & SADEGHIPOUR, HAMID REZA. (2011). ASSESMENT OF FLAXSEED ON OXIDATIVE STRESS IN PREPUBERTAL RATS WITH EXPERIMENTAL VARICOCELE. PHYSIOLOGY AND PHARMACOLOGY, 15(3), 415-426. SID. https://sid.ir/paper/75181/en

Vancouver: Copy

SOHRABIPOUR SHAHLA, JAFARI ADELEH, KAMALINEJAD MOHAMAD, SARRAFNEJD ABDOLFATAH, SHAHRESTANY TAHERAH, SADEGHIPOUR HAMID REZA. ASSESMENT OF FLAXSEED ON OXIDATIVE STRESS IN PREPUBERTAL RATS WITH EXPERIMENTAL VARICOCELE. PHYSIOLOGY AND PHARMACOLOGY[Internet]. 2011;15(3):415-426. Available from: https://sid.ir/paper/75181/en

IEEE: Copy

SHAHLA SOHRABIPOUR, ADELEH JAFARI, MOHAMAD KAMALINEJAD, ABDOLFATAH SARRAFNEJD, TAHERAH SHAHRESTANY, and HAMID REZA SADEGHIPOUR, “ASSESMENT OF FLAXSEED ON OXIDATIVE STRESS IN PREPUBERTAL RATS WITH EXPERIMENTAL VARICOCELE,” PHYSIOLOGY AND PHARMACOLOGY, vol. 15, no. 3, pp. 415–426, 2011, [Online]. Available: https://sid.ir/paper/75181/en

Related Journal Papers