Tubercular Mycobacterial Spindle Cell Pseudotumour: A Case Report

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Dhibar Deba Prasad; Sahu Kamal Kant; SINGH SURJIT; Bal Amanjit; Chougale Abhijit; Dhir Varun

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Journal: IRANIAN JOURNAL OF MEDICAL SCIENCES Year:2018 | Volume:43 | Issue:1 Page(s): 94-96

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Title

Tubercular Mycobacterial Spindle Cell Pseudotumour: A Case Report

Author(s)

Keywords

Acquired immunodeficiency syndrome

Biopsy

Mycobacterium tuberculosis (MTB)

HIV

Spindle cell

Abstract

Pseudotumour is a benign inflammatory lesion. Mycobacterial spindle cell pseudotumour (MSP) is a rare pseudotumour. It is a benign proliferation of spindle-shaped histiocytes containing acidfast mycobacterium, commonly reported in immunocompromised patients. MSP is usually associated with mycobacterium avium complex (MAC). Here, we present the case of a 38-year-old gentleman with acquired immune deficiency syndrome (AIDS) who presented with low-grade fever for 1-month duration. Clinically, he had generalised lymphadenopathy. Chest X-ray showed miliary infiltration in bilateral lung fields. Lymph nodal biopsy showed spindle-shaped histiocytes filled with acid-fast bacilli on Ziehl-Neelsen (ZN) stain, suggestive of MSP. Immunohistochemical (IHC) stains were positive for CD68, S-100 and negative for CD31, which are consistent with MSP. Polymerase chain reaction (PCR) of the biopsy tissue was positive for MTB. Highly active antiretroviral therapy (HAART) was continued and antitubercular therapy (ATT) was started. The fever resolved within two weeks and there was a resolution of lymph nodal swelling by 6 weeks. The diagnosis of MSP associated with mycobacterium tuberculosis (MTB) makes our case interesting. It is of utmost importance to differentiate MSP from Kaposi’ s sarcoma (KS) and other pseudotumours and to know whether it is of tubercular or non-tubercular origin, as the treatment is entirely different.

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APA: Copy

Dhibar, Deba Prasad, Sahu, Kamal Kant, SINGH, SURJIT, Bal, Amanjit, Chougale, Abhijit, & Dhir, Varun. (2018). Tubercular Mycobacterial Spindle Cell Pseudotumour: A Case Report. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), 43(1), 94-96. SID. https://sid.ir/paper/754860/en

Vancouver: Copy

Dhibar Deba Prasad, Sahu Kamal Kant, SINGH SURJIT, Bal Amanjit, Chougale Abhijit, Dhir Varun. Tubercular Mycobacterial Spindle Cell Pseudotumour: A Case Report. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS)[Internet]. 2018;43(1):94-96. Available from: https://sid.ir/paper/754860/en

IEEE: Copy

Deba Prasad Dhibar, Kamal Kant Sahu, SURJIT SINGH, Amanjit Bal, Abhijit Chougale, and Varun Dhir, “Tubercular Mycobacterial Spindle Cell Pseudotumour: A Case Report,” IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), vol. 43, no. 1, pp. 94–96, 2018, [Online]. Available: https://sid.ir/paper/754860/en

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