EFFECTS OF ANTICONVULSANT DRUGS ON THYROID FUNCTION TESTS

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SHIVA S.; ASHRAFI M.R.; MOSTAFAVI F.; ABBASI F.; RABANI ALI

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Journal Paper

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Journal: Iranian Journal of Pediatrics Year:2003 | Volume:13 | Issue:2 Page(s): 101-106

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Information Journal Paper

Title

EFFECTS OF ANTICONVULSANT DRUGS ON THYROID FUNCTION TESTS

Author(s)

Keywords

ANTICONVULSANT DRUGSQ4

THYROID FUNCTION TESTSQ4

THYROID HORMONEQ3

TSHQ4

CONVULSIONQ4

Abstract

Thyroid hormones have critical role in growth and development. Many factors including anti-convulsant drugs affect THYROID HORMONEs. Anti-convulsant drugs are used commonly in children due to high prevalence of seizure disorders in this age group. In order to evaluate THYROID FUNCTION TESTS correctly in these children understanding of drug effects is necessary.In this study, THYROID FUNCTION TESTS of 55 anti convulsant drugs recipients with mean age of 8.88±3.9 year are compared with tests of age and sex matched control group including 42 non drug recipient normal children. Hypothalamic-pituitary axis was assessed with TRH test in 19 patients.Serum T4 level of patients were significantly lower than those of control group (p=0.005). Serum levels of TSH, T3, T3RU and FT4I had no significant difference between the two groups and all of the patients were clinically euthyroid. Hypothalamic-pituitary axis was intact in all of TRH tested patients.In children receiving ANTICONVULSANT DRUGS the serum TSH level is a good indicator of true thyroid function rather than T4 level.

Cites

ANTIEPILEPTIC DRUGS EFFECT ON VITAMIN D STATUS OF EPILEPTIC CHILDREN

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APA: Copy

SHIVA, S., ASHRAFI, M.R., MOSTAFAVI, F., ABBASI, F., & RABANI, ALI. (2003). EFFECTS OF ANTICONVULSANT DRUGS ON THYROID FUNCTION TESTS. IRANIAN JOURNAL OF PEDIATRICS, 13(2), 101-106. SID. https://sid.ir/paper/76125/en

Vancouver: Copy

SHIVA S., ASHRAFI M.R., MOSTAFAVI F., ABBASI F., RABANI ALI. EFFECTS OF ANTICONVULSANT DRUGS ON THYROID FUNCTION TESTS. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2003;13(2):101-106. Available from: https://sid.ir/paper/76125/en

IEEE: Copy

S. SHIVA, M.R. ASHRAFI, F. MOSTAFAVI, F. ABBASI, and ALI RABANI, “EFFECTS OF ANTICONVULSANT DRUGS ON THYROID FUNCTION TESTS,” IRANIAN JOURNAL OF PEDIATRICS, vol. 13, no. 2, pp. 101–106, 2003, [Online]. Available: https://sid.ir/paper/76125/en

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