LEUKOCYTE ADHESION DEFICIENCY; CASE REPORT

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BEHMANESH F.

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Journal Paper

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Journal: Iranian Journal of Pediatrics Year:2007 | Volume:17 | Issue:2 (SUPPLEMENT) Page(s): 311-313

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Title

LEUKOCYTE ADHESION DEFICIENCY; CASE REPORT

Author(s)

BEHMANESH F. | Issue Writer Certificate

Keywords

LEUKOCYTE ADHESIONQ3

INTEGRINQ3

LEUKOCYTOSISQ3

IMMUNODEFFICIENCYQ3

Abstract

Objective: LEUKOCYTE ADHESION deficiency (LAD) disorders, LAD-1 and LAD-2 are rare disease of leukocyte function. LAD-1 results from a lock of leukocyte cell surface expression of β2 INTEGRIN molecules (CD11 & CD18) that are essential for LEUKOCYTE ADHESION to endothelial cells and chemo taxis. Case Presentationt: Our patient a 23-month-old male infant was brought with recurrent skin infections. On examination, the infant was pale with multiple scars in his body. Investigations revealed persisting LEUKOCYTOSIS, serum Immunoglobulin profile and complement were normal. Flow cytometry showed decreased in CD11 and CD18 marker of PMN a diagnosis of LAD1 was made.Conclusion: The accompaniment of persistent LEUKOCYTOSIS and recurrent skin infections will guide us to the primary immune deficiency specially LEUKOCYTE ADHESION deficiency.

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APA: Copy

BEHMANESH, F.. (2007). LEUKOCYTE ADHESION DEFICIENCY; CASE REPORT. IRANIAN JOURNAL OF PEDIATRICS, 17(2 (SUPPLEMENT)), 311-313. SID. https://sid.ir/paper/76167/en

Vancouver: Copy

BEHMANESH F.. LEUKOCYTE ADHESION DEFICIENCY; CASE REPORT. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2007;17(2 (SUPPLEMENT)):311-313. Available from: https://sid.ir/paper/76167/en

IEEE: Copy

F. BEHMANESH, “LEUKOCYTE ADHESION DEFICIENCY; CASE REPORT,” IRANIAN JOURNAL OF PEDIATRICS, vol. 17, no. 2 (SUPPLEMENT), pp. 311–313, 2007, [Online]. Available: https://sid.ir/paper/76167/en

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