EFFECT OF GABAPENTIN ON OPIOID WITHDRAWAL SYMPTOMS IN OPIUM DEPENDENT PATIENTS

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KHEYRABADI GH.R.; RANJKESH M.; MARACI M.R.; SALEHI MEHRDAD

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Journal: Scientific Journal of Kurdistan University of Medical Sciences Year:2008 | Volume:13 | Issue:1 (SERIAL NUMBER 47) Page(s): 13-20

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Information Journal Paper

Title

EFFECT OF GABAPENTIN ON OPIOID WITHDRAWAL SYMPTOMS IN OPIUM DEPENDENT PATIENTS

Author(s)

KHEYRABADI GH.R. | RANJKESH M. | MARACI M.R. | SALEHI MEHRDAD | Issue Writer Certificate

Keywords

GABAPENTINQ3

OPIUM DEPENDENTQ2

WITHDRAWAL SYMPTOMSQ3

OPIOIDQ2

Abstract

Background and Aim: This randomized double-blind, placebo controlled study was performed to evaluate the effectiveness of GABAPENTIN in the treatment of opiate WITHDRAWAL SYMPTOMS.Material and Methods: This was a 3-week double-blind, randomized, placebocontrolled trial and performed in specialized addiction behavior unit, an outpatient unit for the treatment of patients with addiction in Isfahan. The study included forty patients, 37 males and 3 females, between 21-61 years of age who met DSM-IV criteria for opium dependence. The subjects were randomly assigned into 2 groups.The experimental group received MAD (methadone-assisted detoxification) and GABAPENTIN 900 mg/day. Severity of different WITHDRAWAL SYMPTOMS was measured by using subjective opiate withdrawal scale (SWOS) in six steps.Results: Despite superiority of GABAPENTIN to placebo in controlling some of WITHDRAWAL SYMPTOMS no significant difference was noticed between the two groups.Conclusion: Addition of 900 mg/day of GABAPENTIN to MAD treatment regimen is not significantly superior to placebo in controlling opium WITHDRAWAL SYMPTOMS.

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APA: Copy

KHEYRABADI, GH.R., RANJKESH, M., MARACI, M.R., & SALEHI, MEHRDAD. (2008). EFFECT OF GABAPENTIN ON OPIOID WITHDRAWAL SYMPTOMS IN OPIUM DEPENDENT PATIENTS. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 13(1 (SERIAL NUMBER 47)), 13-20. SID. https://sid.ir/paper/76546/en

Vancouver: Copy

KHEYRABADI GH.R., RANJKESH M., MARACI M.R., SALEHI MEHRDAD. EFFECT OF GABAPENTIN ON OPIOID WITHDRAWAL SYMPTOMS IN OPIUM DEPENDENT PATIENTS. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;13(1 (SERIAL NUMBER 47)):13-20. Available from: https://sid.ir/paper/76546/en

IEEE: Copy

GH.R. KHEYRABADI, M. RANJKESH, M.R. MARACI, and MEHRDAD SALEHI, “EFFECT OF GABAPENTIN ON OPIOID WITHDRAWAL SYMPTOMS IN OPIUM DEPENDENT PATIENTS,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 1 (SERIAL NUMBER 47), pp. 13–20, 2008, [Online]. Available: https://sid.ir/paper/76546/en

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