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Information Journal Paper

Title

Single Orbital Metastasis in Castration-Resistant Prostate Cancer (Case Report)

Author(s)

 Garcia Cabezas Sonia | Carmen Moreno Manzanaro Moreno Maria del | Palacios Eito Amalia | Issue Writer Certificate 

Pages

  0-0

Abstract

 Introduction: Orbital metastasis of prostate cancer (PC) is very rare and even more unique in castration-resistant PC (CRPC). In this scenario, choline positron emission tomography/computed tomography (choline PET/CT) is the gold-standard restaging method of choice available in our setting, and new anti-androgens treatments show improvement in overall survival. Case presentation: We report the case of a 69-year-old male patient diagnosed with PC, treated with radical prostatectomy, and salvage radiotherapy after biochemical recurrence. After new prostate-specific antigen (PSA) progression, androgen deprivation therapy (ADT) was started. Four and a half years later, and already labeled as non-metastatic CRPC with a negative extension study, including choline PET/CT, he developed an accidental left frontal head trauma, presenting with proptosis, palpebral oedema, and oculomotor disorder. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a destructive bone lesion in the left orbit, associated with a soft tissue mass. These findings, suggestive of a neoplastic lesion, were histologically confirmed PC metastasis. Treatment was initiated with abiraterone, with a rapid improvement of symptoms, a progressive decrease of PSA, and a significant radiological response. Conclusion: Orbital metastases may present with proptosis and should be considered in patients with a history of cancer. If the ocular-orbital disease is suspected, the nuclear medicine physician should be aware that the choline PET/CT imaging includes the orbits. Tolerability and response to treatment with abiraterone were excellent.

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    Cite

    APA: Copy

    Garcia Cabezas, Sonia, Carmen Moreno Manzanaro Moreno, Maria del, & Palacios Eito, Amalia. (2020). Single Orbital Metastasis in Castration-Resistant Prostate Cancer (Case Report). MULTIDISCIPLINARY CANCER INVESTIGATION, 4(4), 0-0. SID. https://sid.ir/paper/766097/en

    Vancouver: Copy

    Garcia Cabezas Sonia, Carmen Moreno Manzanaro Moreno Maria del, Palacios Eito Amalia. Single Orbital Metastasis in Castration-Resistant Prostate Cancer (Case Report). MULTIDISCIPLINARY CANCER INVESTIGATION[Internet]. 2020;4(4):0-0. Available from: https://sid.ir/paper/766097/en

    IEEE: Copy

    Sonia Garcia Cabezas, Maria del Carmen Moreno Manzanaro Moreno, and Amalia Palacios Eito, “Single Orbital Metastasis in Castration-Resistant Prostate Cancer (Case Report),” MULTIDISCIPLINARY CANCER INVESTIGATION, vol. 4, no. 4, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/766097/en

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