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Information Journal Paper

Title

Role of FDG-PET/CT in Assessing the Correlation Between Blood Pressure and Myocardial Metabolic Uptake

Pages

  36-45

Abstract

 Objective(s): We aimed to assess the association between blood pressure and LV myocardial uptake of FDG, hypothesizing that subjects with raised blood pressure would have higher FDG uptake. Methods: We analyzed 86 healthy controls who underwent PET/CT imaging 180 minutes following FDG (4 MBq/Kg) administration. LV myocardial analysis was performed on axial sections using standard operator guided computer software (OsiriX MD). The average LV myocardial SUVmean (MSUVmean) was calculated for each subject. Subjects were assessed according to the 2017 ACC/AHA guidelines for high blood pressure in adults. Mean arterial blood pressure (MABP) was calculated for each patient. Regression models were employed for statistical analysis. Results: The association of MSUVmean was more pronounced with DP (r=0. 32, p=0. 003) than SP (r=0. 28, p=0. 010); MABP was comparable (r=0. 33, p=0. 002). Correlations of MSUVmean with categorized BPs were: normal SP (r=0. 27, p=0. 010), elevated SP (r=0. 28, p=0. 009), stage 1 SP (r=0. 27, p=0. 010), stage 2 SP (r=0. 28, p=0. 008); normal DP (r=0. 33, p=0. 001), stage 1 DP (r=0. 34, p=0. 001), stage 2 DP (r=0. 35, p=0. 001). Multivariate analysis demonstrated DP (p=0. 006), MABP (p=0. 007), and SP (0. 026). Conclusion: LV myocardial FDG uptake was higher in subjects with elevated blood pressure and correlated positively with SBP and in particular DBP and MABP.

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    Cite

    APA: Copy

    Rojulpote, Chaitanya, Mehdizadeh Seraj, Siavash, Zirakchian Zadeh, Mahdi, Yadav, Divya, Raynor, William Y., Kothekar, Esha, Kothekar, Esha, Kothekar, Esha, Al Zaghal, Abdullah, J. Werner, Thomas, Gerke, Oke, Flemming Hoilund Carlsen, Poul, & Alavi, Abass. (2020). Role of FDG-PET/CT in Assessing the Correlation Between Blood Pressure and Myocardial Metabolic Uptake. ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, 8(1), 36-45. SID. https://sid.ir/paper/766805/en

    Vancouver: Copy

    Rojulpote Chaitanya, Mehdizadeh Seraj Siavash, Zirakchian Zadeh Mahdi, Yadav Divya, Raynor William Y., Kothekar Esha, Kothekar Esha, Kothekar Esha, Al Zaghal Abdullah, J. Werner Thomas, Gerke Oke, Flemming Hoilund Carlsen Poul, Alavi Abass. Role of FDG-PET/CT in Assessing the Correlation Between Blood Pressure and Myocardial Metabolic Uptake. ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY[Internet]. 2020;8(1):36-45. Available from: https://sid.ir/paper/766805/en

    IEEE: Copy

    Chaitanya Rojulpote, Siavash Mehdizadeh Seraj, Mahdi Zirakchian Zadeh, Divya Yadav, William Y. Raynor, Esha Kothekar, Esha Kothekar, Esha Kothekar, Abdullah Al Zaghal, Thomas J. Werner, Oke Gerke, Poul Flemming Hoilund Carlsen, and Abass Alavi, “Role of FDG-PET/CT in Assessing the Correlation Between Blood Pressure and Myocardial Metabolic Uptake,” ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, vol. 8, no. 1, pp. 36–45, 2020, [Online]. Available: https://sid.ir/paper/766805/en

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