مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

115
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

114
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Association of Quality of Life with Serum Phenylalanine Level and Socioeconomic Status in Patients with Phenylketonuria: A Review

Pages

  109-112

Abstract

 Phenylketonuria or PKU has an important place in medical history as the first congenital metabolic disorder. It is a genetic defect in the Phenylalanine hydroxylase enzyme existing in the liver and kidneys which is responsible for the conversion of Phenylalanine to tyrosine. Deficiency of the enzyme results in accumulation of Phenylalanine and its metabolites in the blood and other tissues. If left untreated, mental retardation, speech delays, eczema, seizures, behavioral abnormalities, etc would be expected. In PKU, proper nutrition is the only treatment of choice to prevent complications. The treatment is based on a low-protein Diet, and elimination of all protein-rich foods to prevent severe mental retardation. Dietary changes in PKU are permanent through the life. By controlling the Diet, we reach disease control too. The metabolic control in childhood and adolescence is related to patients’ Quality of life, and their mental status. Even in patients who resume treatment after a period of free Diet, an enhancement in the Quality of life is observed correlated with the Phenylalanine level, in a way that when the Phenylalanine level is between 2 and 6 mg/dL, the patients would have a higher Quality of life. Moreover, the higher the patients’ Phenylalanine level, the lower the Quality of life scores. Similarly, Phenylalanine levels are associated with patients’ social skills. The lower is the patients’ Phenylalanine level, the higher would be the social skills.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    Fooladi, Fatemeh, SOHRABI, ZAHRA, & AKBARZADEH, MARZIEH. (2019). Association of Quality of Life with Serum Phenylalanine Level and Socioeconomic Status in Patients with Phenylketonuria: A Review. INTERNATIONAL JOURNAL OF NUTRITION SCIENCES, 4(3), 109-112. SID. https://sid.ir/paper/770374/en

    Vancouver: Copy

    Fooladi Fatemeh, SOHRABI ZAHRA, AKBARZADEH MARZIEH. Association of Quality of Life with Serum Phenylalanine Level and Socioeconomic Status in Patients with Phenylketonuria: A Review. INTERNATIONAL JOURNAL OF NUTRITION SCIENCES[Internet]. 2019;4(3):109-112. Available from: https://sid.ir/paper/770374/en

    IEEE: Copy

    Fatemeh Fooladi, ZAHRA SOHRABI, and MARZIEH AKBARZADEH, “Association of Quality of Life with Serum Phenylalanine Level and Socioeconomic Status in Patients with Phenylketonuria: A Review,” INTERNATIONAL JOURNAL OF NUTRITION SCIENCES, vol. 4, no. 3, pp. 109–112, 2019, [Online]. Available: https://sid.ir/paper/770374/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button