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Information Journal Paper

Title

EVALUATION OF PLATELET ACTIVATION IN PLATELET CONCENTRATES DURING STORAGE IN THE QUALITY CONTROL LABORATORY OF IRANIAN BLOOD TRANSFUSION ORGANIZATION IN 2004

Pages

  163-169

Abstract

 Background and Objectives Conditions for preparation and storage of platelets for transfusion purposes may lead to platelet activation which in turn contributes to decreased ability of stored platelets to function and to survive in vivo after transfusion as compared with freshly prepared platelets. We investigated platelet membrane expression of CD62P, CD63 in platelet stored for up to 3 days under standard blood banking conditions.  Materials and Methods Twenty-four platelet units prepared by PLATELET-RICH-PLASMA and platelet concentrates were evaluated during storage for markers CD62P, CD63 and pH. Results During storage for up to 3 days platelet units displayed no significant pH (p>0.05). During storage for up to 3 days (days 1 and 3) platelet units were significant in the CD62P and CD63 expressions as compared with day 0 (p<0.05). Conclusions Storage of platelet concentrates causes activated platelets. Moreover, these markers (CD62P and CD63) can act as useful in vitro means in the quality control of platelet components.  

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    APA: Copy

    SOLAIMANY FERIZHANDY, A., AGHAEIPOUR, M., & POURFATH ELAH, A.A.. (2005). EVALUATION OF PLATELET ACTIVATION IN PLATELET CONCENTRATES DURING STORAGE IN THE QUALITY CONTROL LABORATORY OF IRANIAN BLOOD TRANSFUSION ORGANIZATION IN 2004. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 2(5), 163-169. SID. https://sid.ir/paper/78711/en

    Vancouver: Copy

    SOLAIMANY FERIZHANDY A., AGHAEIPOUR M., POURFATH ELAH A.A.. EVALUATION OF PLATELET ACTIVATION IN PLATELET CONCENTRATES DURING STORAGE IN THE QUALITY CONTROL LABORATORY OF IRANIAN BLOOD TRANSFUSION ORGANIZATION IN 2004. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2005;2(5):163-169. Available from: https://sid.ir/paper/78711/en

    IEEE: Copy

    A. SOLAIMANY FERIZHANDY, M. AGHAEIPOUR, and A.A. POURFATH ELAH, “EVALUATION OF PLATELET ACTIVATION IN PLATELET CONCENTRATES DURING STORAGE IN THE QUALITY CONTROL LABORATORY OF IRANIAN BLOOD TRANSFUSION ORGANIZATION IN 2004,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 2, no. 5, pp. 163–169, 2005, [Online]. Available: https://sid.ir/paper/78711/en

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