EFFECT OF METHADONE THERAPY ON QTC INTERVAL IN ELECTROCARDIOGRAM OF OPIOID ADDICTED PATIENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHAKOURI H.; ZEREHSAZ M.J.; FARAJIPOUR S.; SALEHI A.; SALARI H.; MOHAMMADKHANI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download Full-Text

Persian Verion

View:

1,102

Download:

Cites:

Information Journal Paper

Title

EFFECT OF METHADONE THERAPY ON QTC INTERVAL IN ELECTROCARDIOGRAM OF OPIOID ADDICTED PATIENTS

Author(s)

Keywords

OPIOID ADDICTIONQ2

METHADONE THERAPYQ2

ELECTROCARDIOGRAMQ3

QTC INTERVALQ2

Abstract

Background and Objective: Methadone is a synthetic opioid which is used in opium addiction therapy and relief of acute and chronic pain. Side effects of Methadone were reported on heart and induction of Torsade De Pointes disease and increase QTC INTERVAL in ELECTROCARDIOGRAM. This study was conducted to determine the effect of METHADONE THERAPY on QTC INTERVAL in ELECTROCARDIOGRAM and its relationship with dosage and duration of METHADONE THERAPY.Method: This cohort study was conducted on 60 opium addicted patients (57 males, 3 females) whom referred to “Methadone Therapy Clinic” in 5 Azar teaching hospital in Gorgan, northern Iran during 2009-10. Patients were divided to three groups based on the dosage of methadone: 0-35 mg (27 cases), 35-55 mg (27 cases) and 55-120 mg (26 cases) per day. QTC INTERVAL in ELECTROCARDIOGRAM was measured at the beginning of study, one month and 5 months afterward.Results: The mean±SD of QTC INTERVAL in patients at the beginning, one month and 5 months afterward of study was 0.42±0.027, 0.43±0.029 and 0.43±0.041 seconds, respectively. There was a significant increase in QTC INTERVAL after one month of METHADONE THERAPY, compared to the beginning of study. There was no significant difference in QTC INTERVAL between 1 month and 5 months following METHADONE THERAPY. There was no significant difference between QTC INTERVAL and different dosage of methadone.Conclusion: METHADONE THERAPY increase QTC INTERVAL but there is not any relationship between dosage and duration of METHADONE THERAPY and QTC INTERVAL.

Cites

No record.

References

No record.

Cite

APA: Copy

SHAKOURI, H., ZEREHSAZ, M.J., FARAJIPOUR, S., SALEHI, A., SALARI, H., & MOHAMMADKHANI, M.. (2014). EFFECT OF METHADONE THERAPY ON QTC INTERVAL IN ELECTROCARDIOGRAM OF OPIOID ADDICTED PATIENTS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 16(3 (51)), 45-48. SID. https://sid.ir/paper/78797/en

Vancouver: Copy

SHAKOURI H., ZEREHSAZ M.J., FARAJIPOUR S., SALEHI A., SALARI H., MOHAMMADKHANI M.. EFFECT OF METHADONE THERAPY ON QTC INTERVAL IN ELECTROCARDIOGRAM OF OPIOID ADDICTED PATIENTS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;16(3 (51)):45-48. Available from: https://sid.ir/paper/78797/en

IEEE: Copy

H. SHAKOURI, M.J. ZEREHSAZ, S. FARAJIPOUR, A. SALEHI, H. SALARI, and M. MOHAMMADKHANI, “EFFECT OF METHADONE THERAPY ON QTC INTERVAL IN ELECTROCARDIOGRAM OF OPIOID ADDICTED PATIENTS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 3 (51), pp. 45–48, 2014, [Online]. Available: https://sid.ir/paper/78797/en

Related Journal Papers