SEROEPIDEMIOLOGY OF CELIAC DISEASE AMONG BLOOD DONOR IN GOLESTAN PROVINCE

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JOUSHAGHANI H.R.; SEMNANEI SH.; MIR REZAEI A.; ABD ELAHI N.; BESHARAT S.; BEHNAMPOUR N.; DEHBASHI GH.R.; ROUSHANDEL GH.R.

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Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2006 | Volume:8 | Issue:3 (19) Page(s): 44-47

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Title

SEROEPIDEMIOLOGY OF CELIAC DISEASE AMONG BLOOD DONOR IN GOLESTAN PROVINCE

Author(s)

Keywords

ANTIENDOMYSIAL ANTIBODIESQ3

TISSUE TRANSGLUTAMINASEQ3

CELIACQ2

GOLESTANQ3

ESOPHAGUS CANCERQ3

Abstract

Background & Objective: CELIAC is a digestive disease. In this disease, small bowel is damaged and the absorption of nutrients are adversely affected. These patients do not absorb gluten. There is probably a correlation between ESOPHAGUS CANCER and CELIAC. The aim of this research was to study the seroepidemiology CELIAC disease in this area with high prevalence of ESOPHAGUS CANCER.Materials & Methods: This research was a descriptive study, which was performed on blood donors in GOLESTAN province during the year 2005-06. blood samples were taken from 2547 subjects. tTG-IgA determination were carried out using ElISA technique, the titre<4U/ml, 4-10U/ml and> 10Umll were considered to be as negative, weakly positive and positive respectively. EMA antibody assessment was carried out on all sample population with more than 4U/ml, using IFA method.Results: 28 subjects (1.1%) had tTG-Ab positive test, out of this number 18 subjects (0.7%) were weakly positive and 10 persons (0.4%) were considered to be positive. EMA test were positive in 70% of subjects with tTG positive results. There was not any significant meaning between positive tTG test and ethnicity from weakly positive tTG, 15 subjects (83.3%) and 3 subjects (16.7%) were male and female respectively. The entire tTG positive were male subjects. Conclusion: In regard to high prevalence of ESOPHAGUS CANCER in the region and the relation of CELIAC disease with above cancer, it seems necessary to look more seriously at the CELIAC disease.

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References

PREVALENCE OF CEIIAC DISEASE IN NORTH OF IRAN: SCREENING OF AN ADULT POPULATION IN SARI

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APA: Copy

JOUSHAGHANI, H.R., SEMNANEI, SH., MIR REZAEI, A., ABD ELAHI, N., BESHARAT, S., BEHNAMPOUR, N., DEHBASHI, GH.R., & ROUSHANDEL, GH.R.. (2006). SEROEPIDEMIOLOGY OF CELIAC DISEASE AMONG BLOOD DONOR IN GOLESTAN PROVINCE. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 8(3 (19)), 44-47. SID. https://sid.ir/paper/78945/en

Vancouver: Copy

JOUSHAGHANI H.R., SEMNANEI SH., MIR REZAEI A., ABD ELAHI N., BESHARAT S., BEHNAMPOUR N., DEHBASHI GH.R., ROUSHANDEL GH.R.. SEROEPIDEMIOLOGY OF CELIAC DISEASE AMONG BLOOD DONOR IN GOLESTAN PROVINCE. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2006;8(3 (19)):44-47. Available from: https://sid.ir/paper/78945/en

IEEE: Copy

H.R. JOUSHAGHANI, SH. SEMNANEI, A. MIR REZAEI, N. ABD ELAHI, S. BESHARAT, N. BEHNAMPOUR, GH.R. DEHBASHI, and GH.R. ROUSHANDEL, “SEROEPIDEMIOLOGY OF CELIAC DISEASE AMONG BLOOD DONOR IN GOLESTAN PROVINCE,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 8, no. 3 (19), pp. 44–47, 2006, [Online]. Available: https://sid.ir/paper/78945/en

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